Vijay Kumar Saxena
UNIVERSITY OF EASTERN FINLAND, University of Eastern Finland, ICAR-Indian Veterinary Research Institute, Indian Veterinary Research Institute, Indian Veterinary Research Institute Bengaluru Campus
0000-0003-0324-672X
About
A molecular biologist who has been translated to study proteins, their behaviour, functionality and use as therapeutics. In the early part of his research career, he was exposed to solid-phase peptide synthesis, peptide chemistry, and their conjugation and purification technologies. He has gained experience working with different G protein-coupled receptor-like MTNR1A and their role in influencing reproduction in sheep. He was selected for an Indo-Australian career-boosting fellowship which allowed him to work at the Centre of Animal Biotechnology, the University of Melbourne, on an M-cell targeted delivery system for triggering a mucosal immune response. He, along with Dr Jean Pierre Scheerlinck and Alejandra Diaz identified a novel M-cell marker in sheep and developed methods for targeted vaccine delivery. At his laboratory in India, he developed an engineered kisspeptin with an enhanced half-life. Another significant finding from his laboratory includes the identification of an unknown pathway of cysteine synthesis in a multicellular organism of the animal kingdom. He also devised an alternative idea of pyridoxal phosphate permeability in E. coli. He has used protein engineering techniques to improve the properties and function of many therapeutic proteins. He is starting a new group and setting up his Protein Science Laboratory at the School of Pharmacy and would look forward to making further contributions to the research programs of the university. He would like to use his knowledge of antibody-based phage display for using nanobodies for targeted drug delivery systems.
Employment
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UNIVERSITY OF EASTERN FINLAND Senior Scientist2022 - Present
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University of Eastern Finland Senior Researcher2022 - Present
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Indian Veterinary Research Institute Bengaluru Campus Senior Scientist2021 - 2022
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Central Sheep and Wool Research Institute Senior Scientist2018 - 2021
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University of Melbourne Visiting Scientist2016 - 2018
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Central Sheep and Wool Research Institute Scientist2009 - 2016
Education
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ICAR-Indian Veterinary Research Institute Animal Biotechnology2009 - 2015
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Indian Veterinary Research Institute MVSc2006 - 2008
Projects & Funding
Projects & funding information is unavailable.
Publications (39)
- Bioengineered recombinant kisspeptins with extended half-life exhibit novel peripheral function in a large-animal model Save
- Stress Responses to Changing Environmental Factors in the Domestic Animals: An Epigenetic Perspective Save
- Dietary n-3 PUFA augments pre-ovulatory follicle turnover and prolificacy in well-fed ewes Save
- In vitro and in vivo evaluation of Prosopis cineraria (khejri tree) leaves for their preservative potential in minced mutton Save
- Dietary N-3 Pufa Augments Folliculogenesis and Prolificacy in Ewes Maintained at Optimum Nutrition Save
- A novel concept of Pyridoxal 5'-phosphate permeability in E.coli for modulating the heterologous expression of PLP dependent proteins Save
- Pyridoxal 5'-phosphate supplementation modulates the heterologous expression and activity of a PLP dependent model protein in <italic>E.coli</italic> Save
- Effect of nutritional stress on physiological parameters and seminal attributes of native-crossbred ram in semi-arid tropics Save
- Dietary inclusion of nonconventional roughages for lowering enteric methane production and augmenting nutraceutical value of meat in cull sheep Save
- Dietary inclusion of mature lemon grass and curry leaves affects nutrient utilization, methane reduction and meat quality in finisher lambs Save