Velpandian T

About

Thirumurthy Velpandian is a Professor of Pharmacology at All India Institute of Medical Sciences. In 2025, he was elected as a Fellow of the National Academy of Medical Sciences.

His Pharmacology and Clinical Pharmacy Laboratories are engaged in the repurposing and development of drugs for ocular therapeutics. His research group focuses on optimizing and rationalizing drug therapy for various ocular diseases and disorders, including infections & inflammation (uveitis), glaucoma, angiogenesis-related conditions, and diabetic eye complications. The group is also actively involved in investigating the impact of environmental pollutants on human health, with special emphasis on ocular health.

His team continues to explore xenobiotic penetration across blood–ocular barriers by studying transporter susceptibility and utilizing AI/ML-based approaches to predict ocular drug disposition and support pharmacokinetic simulation studies for novel therapeutic agents.

His laboratory is supported by research grants from Indian Council of Medical Research (ICMR), Department of Science and Technology (DST), Department of Biotechnology (DBT), Defence Research and Development Organisation (DRDO), Bill & Melinda Gates Foundation (BMGF), and Biotechnology Industry Research Assistance Council (BIRAC), as well as collaborations with pharmaceutical and startup companies.

His interests and hobbies include bioelectronics, Hindu art and theology, and yoga.

Employment

• All-India Institute of Medical Sciences Professor
  2003 - 2034

Education

• Indira Gandhi National Open University PG Diploma in Intellectual Property Rights
  2018 - 2019
• All India Institute of Medical Sciences PhD
  1994 - 1999
• All-India Institute of Medical Sciences MS (Drug Assay)
  1992 - 1994

Projects & Funding

Projects & funding information is unavailable.

Publications (176)

• Gut microbiome dysbiosis in uveitis – mechanistic insights and emerging therapeutic strategies
  Experimental Eye Research 2026 DOI: 10.1016/j.exer.2026.111073
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• Association of Ayurveda Prakriti, Aspirin-clopidogrel resistance and gene polymorphisms in post-PCI patients: Protocol for a cross-sectional analytical study (Preprint)
  2026 DOI: 10.2196/preprints.108416
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• Synovial Fluid Proteomic Signatures in Different Subtypes of Juvenile Idiopathic Arthritis
  Scandinavian Journal of Immunology 2025 DOI: 10.1111/sji.70051
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• Development and characterization of Dot Blot detection assay for the diagnosis of acanthamoeba keratitis
  Diagnostic Microbiology and Infectious Disease 2025 DOI: 10.1016/j.diagmicrobio.2025.116769
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• Analysis and remediation of phthalates in aquatic matrices: current perspectives
  Environmental Science and Pollution Research 2024 DOI: 10.1007/s11356-024-32670-x
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• Impact of bundled intervention on outcomes of patients undergoing clean orthopedic surgeries with hardware implants: Small prospective randomized controlled trial
  Surg. Infect. (Larchmt) 2023
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• Analysis of the systemic exposure of mitomycin C used in glaucoma filtering surgery among women in the reproductive age group
  Curr. Eye Res. 2023
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• Efficacy and safety of zinc in the prevention of oral mucositis in children with cancer receiving intensified chemotherapy: A randomized double-blind placebo-controlled trial
  Pediatr. Blood Cancer 2023
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• Evaluation of the levels of low dose topical atropine (0.01%) in aqueous and vitreous humor in human eyes
  Optom. Vis. Sci. 2023
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• Untargeted metabolomics in the aqueous humor reveals the involvement of TAAR pathway in glaucoma
  Exp. Eye Res. 2023
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