Sebastian Nijman

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Publications (24)

• Comparison of genetic variants in matched samples using thesaurus annotation.
  2016 DOI: 10.1093/bioinformatics/btv654
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• Parallel reverse genetic screening in mutant human cells using transcriptomics.
  2016 DOI: 10.15252/msb.20166890
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• Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity.
  2016 DOI: 10.1371/journal.pgen.1006279
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• Functional genomics to uncover drug mechanism of action.
  2015 DOI: 10.1038/nchembio.1963
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• Light-assisted small-molecule screening against protein kinases.
  2015 DOI: 10.1038/nchembio.1933
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• NOTCH1 activation in breast cancer confers sensitivity to inhibition of SUMOylation.
  2015 DOI: 10.1038/onc.2014.319
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• A thesaurus of genetic variation for interrogation of repetitive genomic regions.
  2015 DOI: 10.1093/nar/gkv178
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• Targeting a cell state common to triple-negative breast cancers.
  2015 DOI: 10.15252/msb.20145664
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• A generic strategy for CRISPR-Cas9-mediated gene tagging.
  2015 DOI: 10.1038/ncomms10237
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• Synthetic lethal vulnerabilities of cancer.
  2015 DOI: 10.1146/annurev-pharmtox-010814-124511
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