Robert Freeborn

Employment

• Tr1X, Inc Senior Scientist
  2025 - Present
• TR1X, Inc Scientist II
  2023 - 2025
• Stanford University Postdoctoral Fellow
  2020 - 2023
• Genentech Intern
  2019 - 2019
• Michigan State University Graduate Assistant
  2015 - 2020

Education

• Michigan State University Ph. D
  2015 - 2020
• California Polytechnic State University BS
  2011 - 2015

Projects & Funding

Projects & funding information is unavailable.

Publications (14)

• Epigenetic landscape, key transcriptional regulators, and in vivo identification of human Tr1 cells
  Alma‐Martina Cepika, Laura Amaya, Colin Waichler +13 more
  Science Advances 2026 DOI: 10.1126/sciadv.aec6358
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• Arsenic trioxide inhibits the response of primary human B cells to influenza virus A in vitro
  Toxicology in Vitro 2024 DOI: 10.1016/j.tiv.2024.105783
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• Interleukin-10 disrupts liver repair in acetaminophen-induced acute liver failure
  Frontiers in Immunology 2023 DOI: 10.3389/fimmu.2023.1303921
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• AML/T cell interactomics uncover correlates of patient outcomes and the key role of ICAM1 in T cell killing of AML
  2023 DOI: 10.1101/2023.09.21.558911
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• Type 1 regulatory T cell-mediated tolerance in health and disease
  Robert Arthur Freeborn, Steven Strubbe, Maria Grazia Roncarolo
  Frontiers in Immunology 2022 DOI: 10.3389/fimmu.2022.1032575
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• Trivalent arsenic impairs the effector response of human CD4+ and CD8+ T cells to influenza A virus ex vivo
  Food and Chemical Toxicology 2022 DOI: 10.1016/j.fct.2022.113122
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• Interleukin-6 Drives Key Pathologic Outcomes in Experimental Acetaminophen-induced Liver Failure
  2021 DOI: 10.1101/2021.11.15.468664
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• BHLHE40 Regulates IL-10 and IFN-γ Production in T Cells but Does Not Interfere With Human Type 1 Regulatory T Cell Differentiation
  Molly Javier Uyeda, Robert Arthur Freeborn, Brandon Cieniewicz +8 more
  Frontiers in Immunology 2021 DOI: 10.3389/fimmu.2021.683680
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• The Yin and Yang of Type 1 Regulatory T Cells: From Discovery to Clinical Application
  Frontiers in Immunology 2021 DOI: 10.3389/fimmu.2021.693105
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• The role of Nrf2 in autoimmunity and infectious disease: Therapeutic possibilities
  Advances in Pharmacology 2021 DOI: 10.1016/bs.apha.2020.10.003
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• Chronic low-level cadmium exposure in rats affects cytokine production by activated T cells
  Toxicology Research 2019 DOI: 10.1039/c8tx00194d
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• The Nrf2 activator tBHQ inhibits the activation of primary murine natural killer cells
  Food and Chemical Toxicology 2018 DOI: 10.1016/j.fct.2018.08.067
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• Differential effects of the Nrf2 activators tBHQ and CDDO-Im on the early events of T cell activation
  Biochemical Pharmacology 2018 DOI: 10.1016/j.bcp.2017.11.005
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• Inhibition of early T cell cytokine production by arsenic trioxide occurs independently of Nrf2
  PLOS ONE 2017 DOI: 10.1371/journal.pone.0185579
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