Dhirendra K. Singh
University of North Carolina, Umea universitet Institutionen for Molekylarbiologi, Eötvös Loránd University (ELTE), University of Szeged, Amity University
0000-0003-0754-9293
About
My work as a postdoc associate at UNC, Chapel Hill, US is to identify the immune signaling/ pathways to advance the therapeutic interventions of necrotic enterocolitis (NEC) which is a destructive gastrointestinal disease and a leading cause of death in premature infants. To achieve our goal, we are using advanced molecular, immunology-gut immune cell isolation and characterization, and microbiology techniques such as 'Gut-on-a-chip' model, enteroid culture, single-cell sequencing, detection of DNA methylation, ELISA, microbiota analysis, flow cytometry, RNAseq, Confocal microscopy, and others.
Employment
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University of North Carolina Postdoc associate2022 - Present
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Umea universitet Institutionen for Molekylarbiologi Postdoc2020 - 2022
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Amity University Teacher2015 - 2015
Education
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Eötvös Loránd University (ELTE) Visiting Student2018 - Present
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University of Szeged PhD2015 - Present
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Amity University Junior Research Fellow2014 - 2015
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Cochin University of Science and Technology M.Tech2012 - 2014
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Amity University B.Tech2007 - 2011
Projects & Funding
Projects & funding information is unavailable.
Publications (10)
- The gut commensalBlautiamaintains colonic mucus function under low fiber consumption through short-chain fatty acid-mediated activation of Ffar2 Save
- Necrotizing enterocolitis: Bench to bedside approaches and advancing our understanding of disease pathogenesis Save
- Lactobacillus acidophilus, L. plantarum, L. rhamnosus, and L. reuteri Cell-Free Supernatants Inhibit Candida parapsilosis Pathogenic Potential upon Infection of Vaginal Epithelial Cells Monolayer and in a Transwell Coculture System Save
- Characterization of secreted aspartyl proteases in Candida parapsilosis Save
- Functional Characterization of Secreted Aspartyl Proteases in Candida parapsilosis Save
- Minocycline diminishes the rotenone induced neurotoxicity and glial activation via suppression of apoptosis, nitrite levels and oxidative stress Save
- Disruption of Protein Mannosylation Affects Candida guilliermondii Cell Wall, Immune Sensing, and Virulence Save
- Role of microRNA in regulating cell signaling pathways, cell cycle, and apoptosis in non-small cell lung cancer Save
- Regulation of expression of microRNAs by DNA methylation in lung cancer. Save
- Molecular characterization and phylogenetic analysis of Family Adenoviridae from marine environment as inferred from the hexon protein gene Save