Sachith Munasinghe
Emory University, National Hospital of Sri Lanka, University of Colombo
Research areas: Medicine · Gastroenterology · Inflammatory Bowel Disease · Gut microbiota and health · Ocular Diseases and Behçet’s Syndrome
0000-0003-0787-8169
About
I'm a medical graduate from Sri Lanka with a passion for research in immunology and gastroenterology. I earned my MBBS with First Class Honors and 7 distinctions, including all clinical subjects, from the Faculty of Medicine, University of Colombo in 2022. Achieving a top 5 ranking in the country merit list was a notable accomplishment, especially considering the competition among over 1200 graduates in my class of 2022
Following graduation, I trained in general surgery and internal medicine at the National Hospital of Sri Lanka, and later worked in the emergency medicine unit.
My research interests led me to Emory University, where I'm currently a second-year postdoctoral fellow in the Kugathasan Lab. Under the guidance of renowned Inflammatory Bowel Disease expert Dr. Subra Kugathasan, I'm investigating the immune aspects of the disease using cutting-edge techniques such as human intestinal organoids, single-cell analysis, flow cytometry, and immunofluorescence.
I'm enthusiastic about exploring the intersection of immunology and gastroenterology and am open to collaborations. I'm grateful for the opportunities I've had so far and look forward to future adventures.
Employment
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Emory University Post Doctoral Fellow2024 - 2029
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National Hospital of Sri Lanka House Officer2022 - 2023
Education
- 2015 - 2022
Projects & Funding
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Patient based translational research in IBD US National Institutes of Health2026 - Present
Publications (19)
- Prevalence and trends of hypertension among South Asian adults: a systematic review and meta-analysis Save
- DISTINCTIONS IN CD4+ MACROPHAGE BEHAVIOR SIGNIFY CROHN’S DISEASE WITH PERIANAL COMPLICATIONS Save
- A Myeloid Lineage Signifying Anti-tumor Necrosis Factor Resistance in Crohn’s Disease Save
- DECODING CELLULAR CROSSTALK IN INFLAMMATORY BOWEL DISEASE THROUGH DEEP LEARNING-DRIVEN SPATIAL PROTEOMIC AND TRANSCRIPTOMIC MAPPING Save
- DISTINCTIONS IN CD4+MACROPHAGE BEHAVIOR SIGNIFY CROHN'S DISEASE WITH PERIANAL COMPLICATIONS Save
- METABOLIC INFLAMMATION IN CROHN'S DISEASE: EFFECTS OF CARNITINE PAMITOYLTRANSFERASE ACTIVITY ON INFLAMMATORY SIGNALING IN THE INTESTINAL EPITHELIUM Save
- METABOLIC INFLAMMATION IN CROHN'S DISEASE: EFFECTS OF CARNITINE PAMITOYLTRANSFERASE ACTIVITY ON INFLAMMATORY SIGNALING IN THE INTESTINAL EPITHELIUM Save
- PRO-INFLAMMATORY CD4+MACROPHAGE ACTIVITY AND ANTIGEN PROCESSING DURING PERIANAL FISTULIZING CROHN'S DISEASE Save
- Single-Cell and Spatial Transcriptomics Across Populations With Perianal Fistulizing Crohn’s Disease Shows Proinflammatory CD4+ Macrophage Involvement in Disease Progression Save
- TNF-α AND IFN-γ DISRUPT EPITHELIAL CELL MITOCHONDRIAL FUNCTION AND GLUT1 LOCALIZATION DURING ACTIVE CROHN'S DISEASE Save
- Unique challenges faced by tweens and teens with inflammatory bowel disease: a global perspective Save
- Maternal Microchimerism, a Red Flag or a Red Herring in Very-Early-Onset Inflammatory Bowel Disease? Save
- Altered inflammatory mucosal signatures within their spatial and cellular context during active ileal Crohn's disease. Save
- HMG-COA PATHWAYS AS REGULATORS OF IMMUNE RESPONSES IN THE INTESTINAL EPITHELIUM IN CROHNS DISEASE (CD) Save
- MODULATION OF INTESTINAL EPITHELIAL IMMUNE RESPONSES BY HMG-COA PATHWAYS Save
- MODULATION OF INTESTINAL EPITHELIAL IMMUNE RESPONSES BY HMG-COA PATHWAYS Save
- How do we define normal bowel frequency from newborn to teens?: A Bayesian meta-analysis. Save
- Diagnostic pitfalls and therapeutic challenges of hypercalcaemia in chronic kidney disease: a case report and a narrative review Save
- Non-invasive assessment of endothelial dysfunction: A novel method to predict severe COVID-19? Save