Sonal Mahajan
Sanford Burnham Prebys Medical Discovery Institute, Sanford-Burnham Medical Research Institute at UCSB, CSIR - Institute of Microbial Technology, University of Jammu
0000-0003-0864-9528
About
I am a translational cell and molecular biologist specializing in the development of advanced human in vitro disease models to study genetic and developmental disorders. My research integrates patient-derived induced pluripotent stem cell (iPSC) systems and three-dimensional organoid platforms with molecular, biochemical, and phenotypic analyses to investigate disease mechanisms.
I have established and optimized iPSC-derived cartilage organoid models in an academic research setting, enabling the translation of molecular defects into functional cellular phenotypes. My work is grounded in glycobiology and molecular genetics, with an emphasis on understanding extracellular matrix biology and its role in human disease.
My broader research interests focus on leveraging stem cell–based platforms for disease modeling, assay development, and therapeutic exploration, with the goal of advancing translational applications in biotechnology and pharmaceutical research.
Employment
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Sanford Burnham Prebys Medical Discovery Institute Staff Scientist2025 - Present
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Sanford Burnham Prebys Medical Discovery Institute Postdoctoral Associate2021 - 2025
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Sanford-Burnham Medical Research Institute at UCSB Postdoctoral Associate2019 - 2021
Education
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CSIR - Institute of Microbial Technology Doctor of Philosophy2014 - 2019
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University of Jammu Masters in Science2011 - 2014
Projects & Funding
Projects & funding information is unavailable.
Publications (14)
- Patient iPSC-Derived Cartilage Organoids Reveal Defective ECM Deposition and Altered Chondrogenic Trajectory in Saul-Wilson Syndrome Save
- Effect of domain architecture and non-native F-type lectin domains on a Streptosporangium roseum α-L-fucosidase. Save
- Beyond genetics: Deciphering the impact of missense variants in CAD deficiency Save
- Homozygous truncating variant in MAN2A2 causes a novel congenital disorder of glycosylation with neurological involvement Save
- COG4 mutation in Saul-Wilson syndrome selectively affects secretion of proteins involved in chondrogenesis in chondrocyte-like cells. Save
- COG4 mutation in Saul-Wilson Syndrome selectively affects secretion of proteins involved in chondrogenesis in chondrocyte-like cells Save
- Biofilm inhibitory effect of alginate lyases on mucoid P. aeruginosa from a cystic fibrosis patient Save
- Cellulophaga algicola alginate lyase inhibits biofilm formation of a clinical Pseudomonas aeruginosa strain MCC 2081 Save
- Amino acid residues important for D-galactose recognition by the F-type lectin, Ranaspumin-4 Save
- Investigating the pathway of CD8+T-cell apoptosis involving the ST3Gal-I sialyltransferase and Core 1 O-glycan sialylation Save