Hassan Mubarak Ishqi

About

I have completed B.S. and MS. in Biochemistry from AMU, Aligarh, India. During my Ph.D. from the same department, I focused on computational analysis and alternatively spliced transcripts of some cancer-associated genes. Another project involved elucidating the binding mechanisms of various NSAIDs and anticancer drugs with DNA.

Following my Ph.D., I got the opportunity of teaching undergraduate students in the department as an Assistant Professor before joining as a National Postdoctoral Fellow (DST-SERB) at the National Institute of Immunology (NII), New Delhi, India. At NII, the project involved modulation of i6A37 and ms2i6A37 tRNA modifications via the mevalonate pathway. The objective was to look for variations in the translation efficiency using ribosome profiling and RNA seq.

I joined the University of Miami, Florida, USA in March 2021 as a Postdoctoral Associate. Here, I am working on multiple projects on pancreatitis and pancreatic cancer, among which one involves the role of neutrophils and NETs in these diseases. Our group is the developer of the drug Minnelide, which has shown promising results in pancreatic and other cancers. The long-term goal is to determine the potential targets that can be exploited for therapeutic interventions in these diseases.

Employment

• Washington University in St. Louis Postdoctoral Research Associate
  2024 - Present
• Leonard M. Miller School of Medicine, University of Miami Assistant Scientist
  2023 - 2024
• Leonard M. Miller School of Medicine, University of Miami Postdoctoral Associate
  2021 - 2023
• National Institute of Immunology National Postdoctoral Fellow
  2018 - 2020
• Aligarh Muslim University Assistant Professor (Contractual)
  2018 - 2018

Education

• Aligarh Muslim University Ph.D.
  2012 - 2017

Projects & Funding

Projects & funding information is unavailable.

Publications (30)

• Laccase Engineering: Redox Potential Is Not the Only Activity-Determining Feature in the Metalloproteins
  Molecules 2023 DOI: 10.3390/molecules28176209
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• IMPACT OF AGE ON EXPERIMENTAL ACUTE PANCREATITIS AND ITS PROGRESSION
  Gastroenterology 2023
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• Recent advances in the role of neutrophils and neutrophil extracellular traps in acute pancreatitis
  Clinical and Experimental Medicine 2023 DOI: 10.1007/S10238-023-01180-4
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• Increased expression of HPV-E7 oncoprotein correlates with a reduced level of pRb proteins via high viral load in cervical cancer
  Scientific Reports 2023 DOI: 10.1038/s41598-023-42022-3
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• Racial Disparity Between Whites and African Americans in Incidence and Outcome of Pancreatic Cancer: Have We Made a Difference?
  Gastroenterology 2022 DOI: 10.1053/j.gastro.2021.12.256
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• Detection of truncated isoforms of human neuroserpin lacking the reactive center loop: Implications in noninhibitory role
  IUBMB Life 2021 DOI: 10.1002/iub.2475
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• Enzyme engineering: Reshaping the biocatalytic functions
  Biotechnology and Bioengineering 2020 DOI: 10.1002/bit.27329
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• Investigating the mechanism of binding of nalidixic acid with deoxyribonucleic acid and serum albumin: a biophysical and molecular docking approaches
  Journal of Biomolecular Structure and Dynamics 2020 DOI: 10.1080/07391102.2020.1711808
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• Fungal Peroxidases Mediated Bioremediation of Industrial Pollutants
  Fungal Bioremediation: Fundamentals and Applications 2019
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• Differentially expressed novel alternatively spliced transcript variant of tumor suppressor Stk11 gene in mouse
  Gene 2018 DOI: 10.1016/j.gene.2018.05.053
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