JJ
Jiansheng Jiang
National Institutes of Health, Brookhaven National Laboratory, University of York, University of Science and Technology of China, Yale University
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Immunotherapy and Immune Responses · Enzyme Structure and Function · vaccines and immunoinformatics approaches
0000-0003-0964-5481
Employment
- 2006 - Present
- 1996 - 2006
-
Yale University post-doc1991 - 1996
Education
-
University of York Ph.D.1985 - 1989
- 1974 - 1979
Projects & Funding
Projects & funding information is unavailable.
Publications (66)
- Cryo-EM and X-ray structures of an anti-MHC-I monoclonal antibody/H2-Kb complex reveal the basis of conformational dependence and allelic specificity Save
- Antibody Blockade of Ly49/MHC-I interactions enhances Innate and Adaptive Immunity Against Cancer Metastasis Save
- Structural mechanism of anti-MHC-I antibody blocking of inhibitory NK cell receptors in tumor immunity Save
- Antibody-Mediated Inhibition of HLA/LILR Interactions Breaks Innate Immune Tolerance and Induces Antitumor Immunity Save
- Structural mechanism of anti-MHC-I antibody blocking of inhibitory NK cell receptors in tumor immunity Save
- Chaperone-mediated MHC-I peptide exchange in antigen presentation Save
- Experimental Structures of Antibody/MHC-I Complexes Reveal Details of Epitopes Overlooked by Computational Prediction Save
- Experimental structures of antibody/MHC-I complexes reveal details of epitopes overlooked by computational prediction Save
- SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain Save
- Chaperone function in antigen presentation by MHC class I molecules—tapasin in the PLC and TAPBPR beyond Save
- SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain Save
- Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation Save
- Chaperones and Catalysts: How Antigen Presentation Pathways Cope With Biological Necessity Save
- Mucus sialylation determines intestinal host-commensal homeostasis Save
- Structures of synthetic nanobody–SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction Save
- Synthetic nanobody–SARS-CoV-2 receptor-binding domain structures identify distinct epitopes Save
- Structural mechanism of DNA recognition by the p204 HIN domain Save
- Structures of synthetic nanobody–SARS-CoV-2–RBD complexes reveal distinct sites of interaction and recognition of variants Save
- Structural and dynamic studies of TAPBPR and Tapasin reveal the mechanism of peptide loading of MHC-I molecules Save
- MHC‐restricted Ag85B‐specific CD8 + T cells are enhanced by recombinant BCG prime and DNA boost immunization in mice Save