Frank Lohr
APSS, Proton Therapy Center, University of Trento, Heidelberg University, University of Modena and Reggio Emilia
Research areas: Physics and Astronomy · Radiation · Advanced Radiotherapy Techniques · Radiation Therapy and Dosimetry · Radiation Dose and Imaging
About
Prof. Frank Lohr received his medical degree from Heidelberg University, Germany. Residency followed at the Dept. of Radiation Oncology of Heidelberg University and the German Cancer Research Center (dkfz), Heidelberg. During residency, he spent two years in radiobiological research on hyperthermia induced gene therapy at Duke University, NC, USA. Following his residency, he joined the team at the Dept. of Radiation Oncology at University Medical Center Mannheim, University of Heidelberg as attending physician, where he became vice chairman in 2004 and associate adjunct professor in 2005. From 2016 to 2023 he was the director of the Unità Operativa di Radioterapia, Azienda Ospedaliero-Universitaria, Policlinico, Modena and from 2019 to 2023 Associate Professor of the University of Modena and Reggio-Emilia (UniMoRe). He was also the Director of the residency program in Radiation Oncology at UniMoRe. Since 2024 he has been the Director of the Unità Operativa di Protonterapia di Trento and Associate Professor of the University of Trento.
Prof. Lohr has special interest in precision radiotherapy techniques such as Intensity Modulated Radiotherapy (IMRT), Volumetric Arc Therapy (VMAT) (performed the second VMAT treatment in Germany), Image Guided Radiotherapy (IGRT) Stereotactic Body Radiotherapy (SBRT) and total body irradiation (TBI). The department of Radiation Oncology at University Medical Center Mannheim was an early adopter of stereotactic ultrasound technology, Cone-Beam CT (first in Germany) and has explored its use in SBRT and other clinical indications since.
His main clinical interest is in Lung Cancer, Gastric Cancer, Head and neck Tumors, CNS tumors and Prostate cancer where he was the clinical lead for Germany/Austria/Switzerland of the first phase III trial combining Radiotherapy and active Immunotherapy
Going forward, his main interests will be the interdisciplinary optimization of surgery, systemic therapy (particularly Immunotherapy) and radiotherapy as well as the optimization of local radiotherapy based on optimal integration of imaging modalities such as MRI (e.g. IO-Nanoparticles) and PET. In addition, new combined treatment approaches in advanced metastatic disease and oligometastatic disease (e.g. in kidney cancer and ovarian cancer) are of interest.
Prof. Lohr has been lead faculty of international IMRT/VMAT and EMR-courses and observational trainings that are held several times every year at UMM, with a total of more than 500 attendants over the last 10 years and was Co-Director of the ESTRO Course for IMRT that is held annually for more than 100 international participants.
Prof. Lohr has contributed to more than 200 peer-reviewed and medline-listed scientific articles, textbook chapters and textbooks and was co-editor of a German standard radiotherapy textbook. He is reviewer for several international journals and is on the editorial board of “Strahlentherapie und Onkologie”, the journal of the German society for Radiation Oncology (DEGRO) and “Radiation Oncology” and is a member of AIRO and ESTRO.
Employment
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APSS, Proton Therapy Center Director2024 - Present
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University of Trento Associate Professor2024 - Present
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Università degli Studi di Modena e Reggio Emilia Associate Professor and Director of the Radiotherapy Unit2019 - 2023
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Radiation Oncology Center, Mannheim University Hospital, University of Heidelberg Vice Chairman2002 - 2015
Education
Projects & Funding
Projects & funding information is unavailable.
Publications (263)
- A dedicated MKM-based radiobiological model for secondary cancer estimation in charged particle radiotherapy: An application in lymphomas and breast proton therapy Save
- Dose constraints in breast cancer radiotherapy. A critical review Save
- Static proton arc therapy: Comprehensive plan quality evaluation and first clinical treatments in patients with complex head and neck targets Save
- Management of oligometastatic and oligoprogressive epidermal growth factor receptor mutated non-small cell lung cancer patients: state of the art of a combined approach Save
- A Cardiac Motion Model To Evaluate Intra-Fraction Dosimetric Variations In Radiotherapy Treatments Save
- Finite Element Biomechanical Modeling Of Parotid Gland Morphing In Patients Undergoing Radiotherapy For Head and Neck Tumors Save
- Long-term characterization of MRI-morphologic alterations after active motion-compensated liver SBRT: a multi-institutional pooled analysis Save
- Oligorecurrent Non-Small-Cell Lung Cancer Treated by Chemo-Radiation Followed by Immunotherapy and Intracranial Radiosurgery: A Case Report and Mini Review of Literature Save
- Oropharyngeal squamous cell carcinoma: Prognostic factors for development of distant metastases and oncological outcomes Save
- Surface guidance compared with ultrasound-based monitoring and diaphragm position in cone-beam computed tomography during abdominal stereotactic radiotherapy in breath-hold Save
- Validation of RayStation Monte Carlo dose calculation algorithm for multiple LINACs Save
- A systematic review and meta-analysis on oncological radiotherapy in patients with a cardiac implantable electronic device: Prevalence and predictors of device malfunction in 3121 patients Save
- Cosmetic Results and Side Effects of Accelerated Partial-Breast Irradiation Versus Whole-Breast Irradiation for Low-Risk Invasive Carcinoma of the Breast: The Randomized Phase III IRMA Trial Save
- Thoracic Radiotherapy in Extensive Disease Small Cell Lung Cancer: Multicenter Prospective Observational TRENDS Study Save
- Adding Concomitant Chemotherapy to Postoperative Radiotherapy in Oral Cavity Carcinoma with Minor Risk Factors: Systematic Review of the Literature and Meta-Analysis Save
- Motion Management in a Patient With Tracheostomy During Lung Stereotactic Body Radiation Therapy: Breath Hold Is Worth a Try Save
- Stereotactic or conventional radiotherapy for macroscopic prostate bed recurrence: a propensity score analysis Save
- Optimization of Precursor Preparation in PSMA-11 Radiolabeling to Obtain a Highly Reproducible Radiochemical Yield Save
- Radiotherapy and newly approved cancer drugs – A quantitative analysis of registered protocols for drugs approved for the treatment of solid tumors Save
- Health-related quality of life 24 months after prostate cancer diagnosis: An update from the Pros-IT CNR prospective observational study Save