Pankaj Seth
National Brain Research Centre, National Institutes of Health, University of Lucknow, Uniformed Services University of the Health Sciences
0000-0003-1021-7839
About
I am a neurovirologist by training, with interest in understanding the cellular and molecular mechanisms of neurotropic viruses.
My research interests focus around unraveling the molecular mechanisms of HIV-1 and Zika virus induced neuropathogenesis. We use primary cultures of human brain cells, more precisely with human neural stem cells, astrocytes, neurons, oligodendrocytes to understand virus induced neurodegeneration.
In addition to HIV-1 and Zika virus, we have recently started using our in vitro cell culture model of human fetal brain derived cells to understand how SARS-CoV-2 virus and its proteins affect human brain cells.
Employment
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National Brain Research Centre Professor2003 - Present
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National Institutes of Health Staff Fellow2001 - 2003
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Uniformed Services University of the Health Sciences Post Doctoral Fellow1996 - 2001
Education
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University of Lucknow Masters of Science1989 - 1991
Projects & Funding
Projects & funding information is unavailable.
Publications (69)
- NSP4 and ORF9b of SARS-CoV-2 Induce Pro-Inflammatory Mitochondrial DNA Release in Inner Membrane-Derived Vesicles Save
- Sinomenine inhibits amyloid beta-induced astrocyte activation and protects neurons against indirect toxicity Save
- Temporal transcriptome analysis of neuronal commitment reveals the preeminent role of the divergent lncRNA biotype and a critical candidate gene during differentiation Save
- Novel role of mortalin in attenuating HIV-1 Tat mediated astrogliosis Save
- SARS-CoV-2 more than a respiratory virus: Its potential role in neuropathogenesis. Save
- MiRNA-137-mediated modulation of mitochondrial dynamics regulates human neural stem cell fate Save
- Identification and Classification of Hubs in microRNA Target Gene Networks in Human Neural Stem/Progenitor Cells following Japanese Encephalitis Virus Infection Save
- Friends Turn Foe—Astrocytes Contribute to Neuronal Damage in NeuroAIDS Save
- Phosphoinositide-3-kinase inhibition elevates ferritin level resulting depletion of labile iron pool and blocking of glioma cell proliferation Save
- Identification and epigenetic analysis of divergent long non-coding RNAs in multilineage differentiation of human Neural Progenitor Cells Save