Jai Prakash

Employment

• Radboud University Nijmegen Medical Centre Professor and Group Leader
  2025 - Present
• University of Twente Full Professor and Chair
  2021 - 2025
• University of Twente Associate Professor
  2018 - 2021
• University of Twente Tenure Track Assistant/Associate Professor
  2012 - 2017
• Karolinska Institutet Forskarassistent (Assistant Professor)
  2011 - 2012
• BiOrion Technologies BV Vice President Preclinical Research
  2007 - 2011
• University of Groningen Postdoctoral Scientist
  2007 - 2011

Education

• University of Groningen PhD (with distinction)
  2002 - 2006
• All India Institute of Medical Sciences Master (Pharmacology)
  ? - 2002

Projects & Funding

Projects & funding information is unavailable.

Publications (125)

• Precision targeting of stromal states in pancreatic cancer: a clinical perspective
  Trends in Cancer 2026 DOI: 10.1016/j.trecan.2026.07.003
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• Mechanosensing-inspired targeted nanosystem rewires heterogenous cancer-associated fibroblasts via CHIP activation in pancreatic ductal adenocarcinoma
  2026 DOI: 10.21203/rs.3.rs-6606556/v1
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• Engineered cyclic peptide targeting ITGA5 disrupts tumor–stroma interaction to overcome desmoplasia and resistance in pancreatic ductal adenocarcinoma
  Acta Pharmaceutica Sinica B 2026 DOI: 10.1016/j.apsb.2025.10.022
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• Immunostimulatory effects of IL-12 targeted pH-responsive nanoparticles in macrophage-enriched 3D immuno-spheroids in vitro model
  Drug Delivery and Translational Research 2025 DOI: 10.1007/s13346-025-01896-8
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• Biomimetic Tumour Model Systems for Pancreatic Ductal Adenocarcinoma in Relation to Photodynamic Therapy
  International Journal of Molecular Sciences 2025 DOI: 10.3390/ijms26136388
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• Targeted nanomedicine for reprogramming the tumor innate immune system: From bench to bedside
  European Journal of Pharmaceutics and Biopharmaceutics 2024 DOI: 10.1016/j.ejpb.2024.114510
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• The Interplay between Extracellular Matrix Remodeling and Cancer Therapeutics
  Cancer Discovery 2024 DOI: 10.1158/2159-8290.CD-24-0002
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• Repositioning the antihistamine ebastine as an intracellular siRNA delivery enhancer
  International Journal of Pharmaceutics 2023 DOI: 10.1016/j.ijpharm.2023.123348
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• Evaluation of paclitaxel-loaded polymeric nanoparticles in 3D tumor model: impact of tumor stroma on penetration and efficacy
  Drug Delivery and Translational Research 2023 DOI: 10.1007/s13346-023-01310-1
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• Microarchitectural mimicking of stroma-induced vasculature compression in pancreatic tumors using a 3D engineered model
  Bioactive Materials 2023 DOI: 10.1016/j.bioactmat.2022.09.015
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