Manbir Sandhu

Employment

• Manifold AI Solution Director
  2025 - Present

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (5)

• Molecular determinants of ligand efficacy and potency in GPCR signaling
  Science 2023 DOI: 10.1126/science.adh1859
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• Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity
  Nature Communications 2022 DOI: 10.1038/s41467-022-34055-5
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• Dissecting the allosteric networks governing agonist efficacy and potency in G protein-coupled receptors
  2021 DOI: 10.1101/2021.09.14.460253
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• Conformational plasticity of the intracellular cavity of GPCR−G-protein complexes leads to G-protein promiscuity and selectivity
  Proceedings of the National Academy of Sciences 2019 DOI: 10.1073/pnas.1820944116
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• Variable G protein determinants of GPCR coupling selectivity
  Proceedings of the National Academy of Sciences 2019 DOI: 10.1073/pnas.1905993116
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