About

Born 18 April 1966, Tradate (VA). Faculty of Sciences-University of Milano, 1988 degree in Biology, Summa Cum Laude. Post-graduate degree, 1994-1996 PhD in Medical Statistics at University of Milano, Summa Cum Laude. 1989-94 Research fellow, Institute of Pharmacology, Faculty of Sciences-Giovanni Lorenzini Foundation, Milano. 1989-94 Research associate for drug discovery, assay development, high throughput screening and data analysis, Lepetit Research Center (Marion Merrel Dow, USA), Gerenzano (VA). From 1995 Senior Biostatistician, Unit of Medical Statistics and Biometry, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan. 2000-2007 Contract Professor of Biostatistics, Faculty of Statistics, University of Milano-Bicocca. 2000-2004 Executive Committee of the International Society for Clinical Biostatistics. 2004–2008 Task Force Leader Evaluation & Benchmarking, BIOPATTERN Network of Excellence (FP6-2002-IST-1-N° 508803): "Computational Intelligence for Biopattern Analysis in Support of eHealthcare". 2005–2009 Board of the International Biometric Society, Italian Region. From 2007 to 2018 Associate Professor, from 28 December 2018 Full Professor in Medical Statistics (ASN 2012 qualification) at the Faculty of Medicine of the University of Milan, 2009 Cofounder of the IEEE Neural Network Society Special Interest Group Biopattern. From 2008-16 he was biostatistician of the Ethics Committees of Ospedale di Melegnano and Fondazione IRCCS Ca’Granda Ospedale Maggiore Policlinico in Milano. Responsible and participant to national and international project grants with Associazione Italiana per la Ricerca sul Cancro AIRC (scientific testimonial 2018), National Research Council-Polish Academy of Sciences, Italian Ministry of Health, Italian Ministry of the University and Research, European Commission. Biostatistical consultant for the application of bioinformatics in drug discovery and development in industrial biotechnology and pharmaceutical research (Nerviano-MS, Italy; Themis-ICTA, France). Italian Government research consultant for ILVA, Taranto.
His main research fields regarded statistical methods for survival analysis and high-throughput biological assays. Planning of diagnostic and prognostic studies in cancer, cardiovascular diseases, rheumatology, hematology and analysis of the results with special interest on molecular biomarkers and bioprofiles. He is focused on the study of cancer dormancy according to chronic inflammation, developing statistical methods for the extension of generalized linear models with AI methods. Author of more than 200 scientific papers, books, technical reports and conference proceedings (168 full publications on international journals indexed on Scopus, H-index 33, june. 2019). Participation with his research group on Biostatistics for Bionformatics and Clinical Translational Research (BBCTR) of the Fondazione IRCCS Istituto Nazionale dei Tumori (INT) and University of Milano to National and European consortia such as the (ISS-ACC) RNBIO project National Network for Bioinformatics (chair of the Biostatistics for Bioinformatics Group) and the FP6 BIOPTRAIN Marie Curie Early Stage Training Fellowship. He was co-organiser of the EU Lifelong Learning Program Erasmus Intensive Program (IP) 2010-2013: “Interdisciplinary Approaches to Microarray Data Analysis” with the universities of Salerno, Napoli, Warwick and Helsinki and 2017 Erasmus+ TUTORIAL with Central Asia and India. He was panel discussant with FDA delegates in the 3rd International Symposium on Integrated Biomarkers in Cardiovascular Diseases (Seattle, WA, USA / July 9-11, 2008). He was the main organizer of the 8th International Meeting on Computational Intelligence for Bioinformatics and Biostatistics CIBB 2011 (Gargnano del Garda, BS Italy / June 30-July 2, 2011). He is in the Steering Committee of CIBB conferences and Invited Key-Note Speaker in CIBB 2012 in Houston TX at The Methodist Hospital. Organization of CIBB 2014 in Cambridge UK as Finance Chair. Board and invited speaker of the International Biometric Conference 2014 Florence, Italy. In addition to the local/national scientific cooperation, he is working with major research institutions in EU (Institut J.Bordet, Bruxelles, KU Leuven, University of Nottigham, UK) and USA (University of Atlanta, Methodist Hospital Research Institute, Houston TX). From 2017 he is the Statistical Editor of the journal Pharmacological Research. In 2017 he was Independent Scientific Advisor of MyMeleon Inc. Palo Alto CA, USA. 2012-2018 chair of the quality assurance (AQ) of the Medicine & Surgery master course of the University of Milano and member of the quality assurance board (PdQ) of University Vita-Salute San Raffaele (2013-2018). Since 2019 he is in the quality board PdQ of the University of Milano. He is delegate for Open Science in DISCCO, University of Milan. 2018. Cofounder and Steering Board member of the Data Science Research Centre (CRC) UMIL on Big Data research.

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Publications (304)