0000-0003-1353-5867 Employment
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University of Lausanne
Education
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Publications (34)
- The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity Save
- Pancreatic CAF-Derived Autotaxin Drives Autocrine CTGF Expression to Modulate Protumorigenic Signaling Save
- The highly selective and oral phosphoinositide 3-kinase delta (PI3K-δ) inhibitor roginolisib induces apoptosis in mesothelioma cells and increases immune effector cell composition Save
- Targeting T regulatory (Treg) cells in immunotherapy-resistant cancers Save
- IOA-244 is a Non-ATP-competitive, Highly Selective, Tolerable PI3K Delta Inhibitor That Targets Solid Tumors and Breaks Immune Tolerance. Save
- Characterization and translational development of IOA-289, a novel autotaxin inhibitor for the treatment of solid tumors Save
- Autotaxin inhibitor IOA-289 reduces gastrointestinal cancer progression in preclinical models. Save
- A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells. Save
- Control of immune cell function by the unfolded protein response Save
- Autotaxin secretion is a stromal mechanism of adaptive resistance to TGFβ inhibition in pancreatic ductal adenocarcinoma. Save