SB
Søren Besenbacher
Aarhus University, deCODE Genetics Inc
Research areas: Biochemistry, Genetics and Molecular Biology · Genetics · Genetic Associations and Epidemiology · Genomics and Phylogenetic Studies · Genomics and Rare Diseases
0000-0003-1455-1738
Employment
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Aarhus University DVIP-external, External VIP2025 - Present
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Aarhus Universitet Associate Professor2015 - Present
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Aarhus University VIP, Associate Professor2015 - Present
- 2013 - 2015
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Aarhus Universitet Postdoc2011 - 2013
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deCODE Genetics Inc Research scientist2009 - 2011
Education
- ? - 2008
Projects & Funding
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The germline mutation process and its impact on human health Natur og Univers, Det Frie Forskningsråd2016 - 2019
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Integrative Classification of Cancers of Unknown Primary Aarhus Universitets Forskningsfond2016 - 2019
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Disentangling mutation and selection in human evolution Villum Foundation2013 - 2016
Publications (65)
- An alignment-free strategy for circulating tumor DNA detection and tumor fraction estimation from whole-genome sequencing data Save
- Combining mutation detection with fragmentomics features leads to improved tumor-informed ctDNA detection Save
- Cross-dataset pan-cancer detection by correlating cell-free DNA fragment coverage with open chromatin sites across cell types Save
- Determinants of de novo mutations in extended pedigrees of 43 dog breeds Save
- Long-read sequencing of primate testis and human sperm allows identification of recombination events in individuals Save
- Transferable cancer detection from cell-free DNA fragment lengths through extensions of non-negative matrix factorization Save
- A reference-free strategy for circulating tumor DNA detection from whole-genome sequencing data Save
- Estimating Gene Conversion Tract Length and Rate From PacBio HiFi Data Save
- Accurate calling of low-frequency somatic mutations by sample-specific modeling of error rates Save
- Evaluating Bioinformatics Processing of Somatic Variant Detection in cfDNA Using Targeted Sequencing with UMIs Save
- Estimating gene conversion tract length and rate from PacBio HiFi data Save
- Evolution of the germline mutation rate across vertebrates Save
- A method to build extended sequence context models of point mutations and indels Save
- Unsupervised detection of fragment length signatures of circulating tumor DNA using non-negative matrix factorization Save
- Expression patterns and prognostic potential of circular RNAs in mantle cell lymphoma Save
- The mutationathon highlights the importance of reaching standardization in estimates of pedigree-based germline mutation rates Save
- A method to build extended sequence context models of point mutations and indels Save
- Studying mutation rate evolution in primates-a need for systematic comparison of computational pipelines Save
- Mutationathon: towards standardization in estimates of pedigree-based germline mutation rates Save
- The germline mutational process in rhesus macaque and its implications for phylogenetic dating Save