NB
Nicolai Juul Birkbak
Also known as: Nicolai Juul
Aarhus University, The Francis Crick Institute, Technical University of Denmark, University College London Cancer Institute
Research areas: Biochemistry, Genetics and Molecular Biology · Cancer Research · Cancer Genomics and Diagnostics · Cancer Immunotherapy and Biomarkers · Microtubule and mitosis dynamics
0000-0003-1613-9587
Employment
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Aarhus University DVIP-external, External VIP2025 - Present
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Aarhus University VIP, Professor2024 - Present
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Aarhus Universitet Associate Professor, group leader2018 - 2024
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Francis Crick Institute Principal research associate, bioinformatics2014 - 2018
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University College London Cancer Institute Principal research associate2014 - 2018
- 2012 - 2014
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Dana Farber Cancer Institute Post doc2010 - 2012
Education
- 2007 - 2010
Projects & Funding
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Implementing thymic health assessment into routine clinical care in Denmark Sygesikring Danmark2026 - 2029
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How does cancer degrade the immune system? Savvaerksejer Jeppe Juhl og Hustru Ovita Juhls Mindelegat2025 - 2030
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Unraveling Immunosenescence from Single Cell and Spatial data Novo Nordisk Foundation2024 - 2029
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Exploring the association between T-cell clonality and cancer: Utility for screening, relapse detection and immunotherapy response Novo Nordisk Foundation2022 - 2025
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Non-invasive tracking of cancer biology, relapse and therapy response through circulating tumor DNA Aarhus Universitets Forskningsfond2019 - 2023
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Exploiting cancer evolution to develop personalized diagnostics for precision medicine Lundbeckfonden2018 - 2023
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A systems approach to identification of markers that predicts breast cancer response to chemotherapy Villum Fonden2012 - 2014
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A systems biology approach to identify genomic patterns that determine the optimal type of chemotherapy in breast cancer Styrelsen for Forskning og Innovation2010 - 2012
Publications (146)
- Nonlinear Aging of the Human TCR Repertoire Is Influenced by Sex, CMV, and Cancer Save
- Thymic radiation is associated with worse outcomes in patients with NSCLC Save
- Immune profiling of T cells: A comparative analysis of single-cell TCR sequencing using 10X Genomics and Parse Biosciences platforms Save
- Evolutionary characterization of lung cancer metastasis Save
- Thymic health and immunotherapy outcomes in patients with cancer Save
- Thymic health consequences in adults Save
- Retraction Note Save
- Cell-Free DNA-Derived Immune Cell Ratios Uncover Cancer-Associated Systemic Changes Save
- BRCA2 deficiency and replication stress drive APOBEC3-Mediated genomic instability Save
- Endogenous viral elements constitute a complementary source of antigens for personalized cancer vaccines Save
- Transferable cancer detection from cell-free DNA fragment lengths through extensions of non-negative matrix factorization Save
- DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution Save
- Advancing circulating tumor DNA detection Save
- FaceAge, a deep learning system to estimate biological age from face photographs to improve prognostication Save
- Low T cell diversity associates with poor outcome in bladder cancer Save
- ImmuneLENS characterizes systemic immune dysregulation in aging and cancer Save
- Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma Save
- Comprehensive genomic characterization of early-stage bladder cancer Save
- TRACERx analysis identifies a role for FAT1 in regulating chromosomal instability and whole-genome doubling via Hippo signalling Save
- Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma Save