Dr. Amrita Singh
Indo Soviet Friendship College of Pharmacy, Guru Ghasidas University
0000-0003-1890-7527
About
Dr. Amrita Singh, Ph.d., M.Pharm (Pharmacology) is working as Associate Professor in Department of Pharmacology at ISF College of Pharmacy, Moga, Punjab, India.
Research Interest:
I firmly believe that today’s health challenges can be addressed by collaborative perspectives with disappearing subject boundaries. Metabolic disorders like diabetes are inherently complex disorder and needs multidisciplinary research approach encompassing of biochemical, molecular and electrophysiological tools for the better understanding of the diabetic secondary complications including cataract and neurobiological impairments. Various neuro-chemical and signaling pathways involved in neuropathological conditions. As an researcher and a faculty, my interest is to establish a collaborative research program in diabetic investigation and its secondary complications focusing on eye related complications, behavioral and molecular neuroscience dedicated to understanding the various signaling pathways involved in eye diseases and neurodegenerative disorders so that better drug candidates can be developed by targeting the disrupted ocular and neuro-machinery.
Current background: I have been trained in different behavioral, biochemical and molecular biology techniques to study the signaling pathways involved in diabetes and its secondary complications like occular and neurodegenerative disorders. During my PhD in metabolic disorders, I was able to identify key signaling pathways involved in diabetes and associated cognitive deficits and diabetic cataract. My PhD research work was published in peer reviewed international journals such as Journal of biochemical and molecular toxicology, Current eye research, Journal of traditional and complementary medicines, Pharma nutrition & Journal of current ophthalmology and is being cited. Apart from this I also studied the role of AMPK/SIRT1, IP3/Ca2+ signaling and phosphodiesterases in diabetic associated neurodegeneration and cardiomyopathy which is currently a big clinical problem.
Employment
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Indo Soviet Friendship College of Pharmacy Associate Professor2021 - Present
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Guru Ghasidas University PhD (ICMR-Senior Research Fellow)2015 - 2021
Education
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Guru Ghasidas University M.Pharm2013 - 2015
Projects & Funding
Projects & funding information is unavailable.
Publications (13)
- Oxymatrine and insulin resistance: Focusing on mechanistic intricacies involve in diabetes associated cardiomyopathy via SIRT1/AMPK and TGF‐β signaling pathway Save
- Resveratrol attenuates behavioural impairment associated with learning and memory in rats with diabetes induced by a high‐fat diet and streptozotocin Save
- Inside the diabetic brain: Insulin resistance and molecular mechanism associated with cognitive impairment and its possible therapeutic strategies Save
- Potential role of IP3/Ca2+ signaling and phosphodiesterases: Relevance to neurodegeneration in Alzheimer’s disease and possible therapeutic strategies Save
- Topical Administration of ACE Inhibitor Interrupts the Progression of Cataract in Two Kidney One Clip Induced Hypertensive Cataract Model Save
- Role of the renin–angiotensin system in the development of cataract formation in angiotensin‐II‐induced experimental rats Save
- Biochemical Evidence Indicates the Preventive Effect of Resveratrol and Nicotinamide in the Treatment of STZ-induced Diabetic Cataract Save
- Resveratrol delay the cataract formation against naphthalene‐induced experimental cataract in the albino rats Save
- Magnesium taurate attenuates progression of hypertension and cardiotoxicity against cadmium chloride-induced hypertensive albino rats Save
- Protective effect of alpha-lipoic acid on progression of cataract formation in fructose-induced experimental cataract Save