MK
Manju Kumari
University Hospital Heidelberg, Heidelberg, DE, University Medical Center Hamburg-Eppendorf, Karl-Franzens-Universitat Graz, Harvard University
0000-0003-1968-2462
Employment
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University Hospital Heidelberg, Heidelberg, DE Junior Group Leader2021 - Present
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University Medical Center Hamburg-Eppendorf Alexander von Humboldt Research Fellow2017 - 2021
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Harvard University Postdoctoral Research Fellow2012 - 2017
Education
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Karl-Franzens-Universitat Graz PhD2007 - 2012
Projects & Funding
Projects & funding information is unavailable.
Publications (25)
- Serum Response Factor (SRF) promotes actin cytoskeletal organization in adipocytes to support adaptive hypertrophic expansion and tissue remodeling during obesity in mice. Save
- Activation of IRF3 in cardiomyocytes impairs mitochondrial oxidative function through PGC-1α inhibition and drives heart failure Save
- Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b. Save
- IRF3 reduces adipose thermogenesis via ISG15-mediated reprogramming of glycolysis Save
- Adipocytes fail to maintain cellular identity during obesity due to reduced PPARγ activity and elevated TGFβ-SMAD signaling Save
- The P2X7 ion channel is dispensable for energy and metabolic homeostasis of white and brown adipose tissues. Save
- Warming Induces Significant Reprogramming of Beige, but Not Brown, Adipocyte Cellular Identity. Save
- Regulation of immunometabolism in adipose tissue. Save
- Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity. Save
- Adipocyte glucocorticoid receptor is important in lipolysis and insulin resistance due to exogenous steroids, but not insulin resistance caused by high fat feeding. Save