MT
Megha Thakur
Catamaran Bio, The University of Texas at Austin, Rajiv Gandhi University of Health Sciences, Biocon Bristol-Myers Squibb Research and Development Center
Research areas: Medicine · Dermatology · Skin Protection and Aging · Nonmelanoma Skin Cancer Studies · Fibroblast Growth Factor Research
0000-0003-2001-0065
Employment
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Catamaran Bio Scientist2023 - Present
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The University of Texas at Austin Ph.D student2017 - 2023
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Biocon Bristol-Myers Squibb Research and Development Center Associate Scientist2010 - 2015
Education
- 2008 - 2010
Projects & Funding
Projects & funding information is unavailable.
Publications (9)
- Drug Delivery Strategy Exploiting Amino Acid Prodrugs: Improving Oral Bioavailability and Overcoming Nonlinear Pharmacokinetic Challenges Following Dose Escalation of a CK2 Inhibitor with Poor Solubility Save
- Enhancing the Oral Bioavailability of a Poorly Soluble Pan-CK2 Kinase Inhibitor: Leveraging a Phosphate Prodrug Strategy to Overcome Dissolution-Limited Absorption and Improve Systemic Exposure during Dose Escalation Save
- Inducible Keratinocyte Specific FGFR2 Deficiency Inhibits UVB-Induced Signaling, Proliferation, Inflammation, and Skin Carcinogenesis Save
- Inhibition of Fibroblast Growth Factor Receptor Attenuates UVB-Induced Skin Carcinogenesis Save
- Mutation in DNA Polymerase Beta Causes Spontaneous Chromosomal Instability and Inflammation-Associated Carcinogenesis in Mice. Save
- Aberrant DNA Polymerase Beta Enhances H. pylori Infection Induced Genomic Instability and Gastric Carcinogenesis in Mice. Save
- Design, Synthesis, and Pharmacokinetic Evaluation of Phosphate and Amino Acid Ester Prodrugs for Improving the Oral Bioavailability of the HIV-1 Protease Inhibitor Atazanavir. Save
- Loss of NEIL3 DNA glycosylase markedly increases replication associated double strand breaks and enhances sensitivity to ATR inhibitor in glioblastoma cells. Save
- A simplified protocol employing elacridar in rodents: a screening model in drug discovery to assess P-gp mediated efflux at the blood brain barrier. Save