James J Gilchrist

Employment

• University of Oxford

Education

Education history is unavailable.

Projects & Funding

• Genetic causes and epigenetic consequences of infection in childhood. Wellcome
  2025 - 2031

Publications (37)

• Genome-wide association study of conjugated pneumococcal vaccine antibody responses in South African infants
  npj Vaccines 2026 DOI: 10.1038/s41541-026-01585-8
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• Host genetic determinants of rotavirus disease and immunity in African children
  2026 DOI: 10.21203/rs.3.rs-10565996/v1
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• Genetic determinants of cytokine production in activated human monocytes
  2026 DOI: 10.64898/2026.05.08.26352736
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• African-specific genetic loci determine iron status and risk of severe malaria and bacteremia in African children
  Nature Communications 2026 DOI: 10.1038/s41467-026-71567-w
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• Genetic determinants of monocyte splicing are enriched for disease susceptibility loci
  Isar Nassiri, James J. Gilchrist, Orion Tong +6 more
  Nature Communications 2025 DOI: 10.1038/s41467-025-63624-7
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• Defining the genetic determinants of CD8+ T cell receptor repertoire in the context of immune checkpoint blockade
  Science Advances 2025 DOI: 10.1126/sciadv.adu3461
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• African-specific genetic loci determine iron status and risk of severe malaria and bacteremia in African children
  2025 DOI: 10.21203/rs.3.rs-6853969/v1
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• Relation Between the Dantu Blood Group Variant and Bacteremia in Kenyan Children: A Population-Based Case-Control Study.
  The Journal of infectious diseases 2025 DOI: 10.1093/infdis/jiae339
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• Altered IL-6 signalling and risk of tuberculosis: a multi-ancestry mendelian randomisation study
  Fergus Hamilton, Haiko Schurz, Tom Yates +97 more
  The Lancet Microbe 2025 DOI: 10.1016/S2666-5247(24)00162-9
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• Vitamin D may influence disease course in PIMS‐TS/MIS‐C: An observational cohort study
  Pediatrics International 2025 DOI: 10.1111/ped.70241
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• Defining the genetic determinants of CD8+T cell receptor repertoire in the context of immune checkpoint blockade
  2024 DOI: 10.1101/2024.11.04.618564
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• Cytomegalovirus infection protects against metastatic melanoma and modulates oncological outcome and toxicity to checkpoint immunotherapy
  2024 DOI: 10.1101/2024.10.09.24315144
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• Genetic determinants of monocyte splicing are enriched for disease susceptibility loci including for COVID-19
  2024 DOI: 10.21203/rs.3.rs-4660781/v1
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• Characterization of the genetic determinants of context-specific DNA methylation in primary monocytes.
  Cell genomics 2024 DOI: 10.1016/j.xgen.2024.100541
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• Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture
  Haiko Schurz, Vivek Naranbhai, Tom Yates +7 more
  eLife 2024 DOI: 10.7554/eLife.84394
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• A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy.
  American journal of human genetics 2024 DOI: 10.1016/j.ajhg.2023.12.013
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• Intracranial Empyema in Children: A Single-center Retrospective Case Series
  Pediatric Infectious Disease Journal 2023 DOI: 10.1097/INF.0000000000004064
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• Characterisation of the genetic determinants of context specific DNA methylation in primary monocytes
  2023 DOI: 10.1101/2023.05.17.541041
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• Altered IL-6 signalling and risk of tuberculosis disease: a meta-analysis and Mendelian randomisation study
  2023 DOI: 10.1101/2023.02.07.23285472
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• Deep sequencing of the T cell Receptor reveals common and reproducible CD8+signatures of response to checkpoint immunotherapy
  2023 DOI: 10.1101/2023.02.11.528080
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