Shine Devarajan
Shine, SIES-IIEM, Karunya Institute of Technology and Sciences, Global Open University, Mahatma Gandhi University
0000-0003-2133-8011
About
Objective
To become a successful professional in the field of Bioinformatics and Structural biology to work on challenging and interdisciplinary computational problems with an opportunity to prove and enhance my skill sets.
Work Experience
Working as an Assistant Professor at the Department of Biotechnology and Bioinformatics, Padmashree Dr. D.Y Patil University, Navi Mumbai (since 15 March 2006 – till date).
Worked as Junior Research Fellow at SIES-IIEM, Nerul, Navi Mumbai- A DBT funded project on ‘in silico analysis of anti-cancer drug Camptothecin and its analogues based on rational drug design’ using MOE and DS modeling packages (July 2005-Feb 2006).
Worked as a Project Trainee at National Chemical Laboratory (NCL), Pune- A project on ‘QSAR analysis on anti-AIDS drug compounds and chemical databases’ using MOE software. (Dec 2004-Mar2005)
Areas of Research & Academic Interest
Molecular Dynamics and Simulation, Protein Structures & folding, Chemical databases and QSAR analysis, Systems Biology, Medicinal Chemistry, Cheminformatics, Sequence analysis, Computational Biology, Pharmacophore Identification, Data Mining, Bioinformatics Software and applications used in computational chemistry.
Skill Set
Biosoftwares : MOE, GROMACS, AutoDock, DS package, VMD, EMBOSS, DS Visualizer, Swiss PDB Viewer, Hex, Argus lab, Flex etc.,
Working knowledge in various Web servers for analyzing structural data and gene expression study. Guided ten B. Tech Bioinformatics students for final year project, currently more than five projects are ongoing in this field.
Molecular Dynamics and Simulation studies of Biological molecules and membranes.
Homology modeling and gene expression studies.
Molecular modeling studies of anti cancer chemical compounds using MOE software & DS package.
Virtual screening of anti cancer compounds.
Operating System expertise: Linux/Ubuntu/Windows
Employment
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SIES-IIEM J.R. F2015 - 2016
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Shine Assistant Professor2006 - Present
Education
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Karunya Institute of Technology and Sciences Ph.D2010 - 2016
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Global Open University M.Phil2009 - 2010
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Mahatma Gandhi University MSc Bioinformatics2002 - 2004
Projects & Funding
Projects & funding information is unavailable.
Publications (18)
- Drug repurposing—an emerging strategy in cancer therapeutics Save
- One of the 5-aminosalicylates drug, mesalamine as a drug repurposing lead against breast cancer Save
- Synergistic combination of ritonavir and cisplatin as an efficacious therapy in human cervical cancer cells: a computational drug discovery and in vitro insight Save
- Therapeutic potential of autophagy activators and inhibitors in lung and breast cancer- a review Save
- Functional relevance of Gedunin as a bona fide ligand of NADPH oxidase 5 and ROS scavenger: An in silico and in vitro assessment in a hyperglycemic RBC model Save
- Drug repurposing: An emerging tool to accelerate the drug development process Save
- In silico and in vitro analysis reveal multi-target anti-hyperglycaemic properties of gedunin, a limonoid from neem (Azadirachta indica) Save
- Identification of Potential Lead Molecules for Zika Envelope Protein from In Silico Perspective. Save
- A Review of the Predictive Aspects of Breast Cancer among Women Save
- Computational studies on the identification of potential leads from Wine polyphenols for Metabotropic Glutamate Receptor 4 (mGluR4) Save