Ranjita Devi Moirangthem

About

I have a passion in scientific research and would like to share my passion and excitement with others for the successful advancement of clinical applications with research interests in Cancer prevention and therapy, Immunotherapy, Stem cell therapy, Regenerative medicine with a main objective of improving human welfare.

Employment

• Imagine Institute for Genetic Diseases Post doctoral researcher
  2016 - Present

Education

• National Centre for Cell Science Ph.D in Biotechnology
  2009 - 2016
• University of Calicut MSc. in Biotechnology
  2007 - 2009

Projects & Funding

Projects & funding information is unavailable.

Publications (11)

• A DL-4- and TNFα-based culture system to generate high numbers of nonmodified or genetically modified immunotherapeutic human T-lymphoid progenitors.
  Cellular & molecular immunology 2021 DOI: 10.1038/s41423-021-00706-8
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• Ex vivo generated human T-lymphoid progenitors as a tool to accelerate immune reconstitution after partially HLA compatible hematopoietic stem cell transplantation or after gene therapy
  2019
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• Baboon envelope LVs efficiently transduced human adult, fetal, and progenitor T cells and corrected SCID-X1 T-cell deficiency.
  Blood advances 2019 DOI: 10.1182/bloodadvances.2018027508
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• Microvesicles Secreted by Nitric Oxide-Primed Mesenchymal Stromal Cells Boost the Engraftment Potential of Hematopoietic Stem Cells.
  Sapana S. Jalnapurkar, Ranjita Devi Moirangthem, Shweta Singh +2 more
  Stem cells (Dayton, Ohio) 2018 DOI: 10.1002/stem.2912
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• Generation of adult human T-cell progenitors for immunotherapeutic applications.
  The Journal of allergy and clinical immunology 2017 DOI: 10.1016/j.jaci.2017.10.034
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• Nitric oxide has contrasting age-dependent effects on the functionality of murine hematopoietic stem cells.
  2016
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• AKT Signaling Prevailing in Mesenchymal Stromal Cells Modulates the Functionality of Hematopoietic Stem Cells via Intercellular Communication.
  Shweta Singh, Ranjita Devi Moirangthem, Anuradha Vaidya

  +3 more

  • Sapana S. Jalnapurkar
  • Lalita S. Limaye
  • Vaijayanti Prakash Kale
  2016 DOI: 10.1002/stem.2409
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• Hypoxic niche-mediated regeneration of hematopoiesis in the engraftment window is dominantly affected by oxygen tension in the milieu.
  2015 DOI: 10.1089/scd.2015.0112
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• Role of FAK signaling in the regulation of HSC expansion.
  “8th Indo-Australia Biotechnology Conference on Stem Cell Biology” 2011
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• Ex vivo generated human T-lymphoid progenitors as a tool to accelerate immune reconstitution after partially HLA compatible hematopoietic stem cell transplantation or after gene therapy
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• Generation of gene corrected T cell progenitors from transduced human cord blood (CB) or mobilized peripheral blood (mPB) CD34 + Hematopoietic Stem and Progenitor cells (HSPCs) using immobilized Delta 4 culture system with TNFα supplementation.
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