smit kour

Employment

Employment history is unavailable.

Education

• University of Nebraska Medical Center Ph.D.
  2016 - 2020

Projects & Funding

Projects & funding information is unavailable.

Publications (14)

• Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth
  Proceedings of the National Academy of Sciences 2022 DOI: 10.1073/pnas.2115071119
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• Spirocyclic dimer SpiD7 activates the unfolded protein response to selectively inhibit growth and induce apoptosis of cancer cells
  Journal of Biological Chemistry 2022 DOI: 10.1016/j.jbc.2022.101890
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• Symbiotic prodrugs (SymProDs) dual targeting of NFkappaB and CDK
  Chemical Biology & Drug Design 2020 DOI: 10.1111/cbdd.13684
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• CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax
  Molecular Pharmacology 2019 DOI: 10.1124/mol.119.116855
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• Selective degradation of CDK6 by a palbociclib based PROTAC
  Bioorganic & Medicinal Chemistry Letters 2019 DOI: 10.1016/j.bmcl.2019.03.035
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• Chemical Genetic Screens Identify Kinase Inhibitor Combinations that Target Anti-Apoptotic Proteins for Cancer Therapy
  ACS Chemical Biology 2018 DOI: 10.1021/acschembio.8b00077
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• Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy.
  Oncotarget 2017 DOI: 10.18632/oncotarget.23749
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• Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC)
  Chemical Communications 2017 DOI: 10.1039/C7CC03879H
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• Long-circulatory nanoparticles for gemcitabine delivery: Development and investigation of pharmacokinetics and in-vivo anticancer efficacy
  European Journal of Pharmaceutical Sciences 2016 DOI: 10.1016/j.ejps.2016.07.007
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• Iodobenzene diacetate-mediated isomerization of pyrazolyl chalcones and their cytotoxicity and anti-microbial activity
  Journal of Chemical Sciences 2015 DOI: 10.1007/s12039-015-0791-4
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