About

Professor,
Department of Biomedical Science,
Acharya Narendra Dev College, University of Delhi, India

My group focuses on bacteriophages and the encoded lytic enzymes as alternatives/adjuncts to antibiotics. We have purified over 200 mycobacteriophages and several mycobacteriophage-derived endolysins as potential therapeutic candidates against Tuberculosis and Non-tuberculous Mycobacterial (NTM) infections. We also work on discovering small-molecule inhibitors as drug candidates that target Mur enzymes in M. tuberculosis.

Employment

Employment history is unavailable.

Education

Education history is unavailable.

Projects & Funding

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Publications (31)

  • Mycobacteriophages: Therapeutic Approach for Mycobacterial Infections.
    Drug Discovery Today 2024
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  • Insights into the genomic features and lifestyle of B1 subcluster mycobacteriophages.
    Journal of Basic Microbiology 2024
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  • Genome announcement and analysis of five new mycobacteriophages belonging to the F, G, K, and P clusters
    BioRxiv 2024
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  • Bacteriophages: The natural combatants to fight AMR
    Emerging Paradigms for Antibiotic-Resistant Infections: Beyond the Pill 2024
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  • Unlocking prophage potential: In silico and experimental analysis of a novel Mycobacterium fortuitum LysinB containing a peptidoglycan-binding domain
    BioRxiv 2024
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  • Discovery and Characterization of a Novel LysinB from F2 Sub-Cluster Mycobacteriophage RitSun
    Scientific Reports 2024
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  • Beyond antibiotics: Phage-encoded lysins against Gram-negative pathogens.
    Frontiers in Microbiology 2023
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  • Phage-encoded lysins as promising antibacterials against uropathogenic Escherichia coli.
    JAC Antimicrobial resistance 2023
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  • ). Identification of Perturbed Pathways Rendering Susceptibility to Tuberculosis in Type 2 Diabetes Mellitus Patients Using BioNSi Simulation of Integrated Network of Implicated Human Genes
    Journal of Biosciences 2022
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  • Alternative Treatment of Secondary Bacterial and Fungal Infections Associated with Covid-19
    Infectious Disease Therapy 2022
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