Prof. Dhruv Kumar
UPES University, Dehradun, Uttarakhand, India, Amity University Uttar Pradesh, Noida, India, SRM University, Delhi-NCR
0000-0003-2586-9397
About
The primary research interest of our laboratory is Translational Cancer Research and to investigate altered metabolic states in several cancers, including Head and Neck, Brain, Breast, Prostate and Pancreatic cancer. Our lab is focused on understanding the molecular mechanism (s) of the regulation of Autophagy and Apoptosis in Cancer Stem Cells (Prostate, Pancreatic and Breast). Specifically, to understand the molecular mechanism (s) of induced Autophagy in Cancer Stem Cells (CSCs) via PI3K/Akt/mTOR signaling pathways. Our lab is also working on molecular cross-talk between tumor microenvironment (Cancer Associated Fibroblast (CAF)) and cancer/cancer stem cells, mutational heterogeneity in solid tumor, exosome secretion from cancer and cancer stem cells and it's role in tumor progression.
Employment
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UPES University, Dehradun, Uttarakhand, India Professor2022 - Present
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Amity University Uttar Pradesh, Noida, India Associate Professor2017 - 2022
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SRM University, Delhi-NCR Assistant Professor2016 - 2017
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University of Kansas Medical Center (KUMC), USA Postdoctoral Fellow2012 - 2016
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (223)
- Effect of casein to fat ratio of camel milk on solids losses in cheese whey and their recovery in camel milk cheese Save
- Six years of conservation agriculture and nutrient management in maize–mustard rotation: Impact on soil properties, system productivity and profitability Save
- Identification of FOXM1 as druggable oncogenic target and Mogroside-V/Mogrol as lead inhibitors in Ovarian cancer Save
- Transcriptomic and network analysis identifies an FGFR3 dysregulation associated with SLC2A1 mediated glycolytic reprogramming in LUSC Save
- Genomic alterations and their correlation with metabolic-related genes in lung cancer Save
- Detection of pesticides in biological samples and linked gallbladder cancer in the population of Bihar, India Save
- Impact of MYC on metabolic reprogramming, cellular energetics, and tumorigenesis in Breast cancer Save
- Genomic and molecular landscape of gallbladder cancer elucidating pathogenic mechanisms novel therapeutic targets and clinical implications Save
- Molecular heterogeneity and MYC dysregulation in triple-negative breast cancer: genomic advances and therapeutic implications Save
- Nanoengineered electrochemical biosensors: a next-gen technology in cancer biomarker detection Save