Sushma Sharma

Employment

• Umeå University Postdoc
  2010 - Present

Education

• Institute of Microbial Technology CSIR Ph.D
  2004 - 2010
• Panjab University B.Sc and M.Sc (Zoology honors)
  1998 - 2003

Projects & Funding

Projects & funding information is unavailable.

Publications (39)

• RRM2B deficiency causes dATP and dGTP depletion through enhanced degradation and slower synthesis
  Proceedings of the National Academy of Sciences 2025 DOI: 10.1073/pnas.2503531122
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• Metabolic tuning enables immediate adaptation to energy stress in yeast
  2025 DOI: 10.1101/2025.06.06.658098
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• Physical interactions between specifically regulated subpopulations of the MCM and RNR complexes prevent genetic instability
  PLOS Genetics 2024 DOI: 10.1371/journal.pgen.1011148
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• Chl1 helicase controls replication fork progression by regulating dNTP pools
  Life Science Alliance 2022 DOI: 10.26508/lsa.202101153
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• Proofreading deficiency in mitochondrial DNA polymerase does not affect total dNTP pools in mouse embryos
  Nature Metabolism 2020 DOI: 10.1038/s42255-020-0264-z
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• Elimination of rNMPs from mitochondrial DNA has no effect on its stability.
  Proceedings of the National Academy of Sciences of the United States of America 2020 DOI: 10.1073/pnas.1916851117
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• High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase.
  Nucleic acids research 2020 DOI: 10.1093/nar/gkaa103
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• SAMHD1 Limits the Efficacy of Forodesine in Leukemia by Protecting Cells against the Cytotoxicity of dGTP.
  Cell reports 2020 DOI: 10.1016/j.celrep.2020.107640
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• Mec1 Is Activated at the Onset of Normal S Phase by Low-dNTP Pools Impeding DNA Replication.
  Molecular cell 2020 DOI: 10.1016/j.molcel.2020.02.021
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• Proofreading deficiency in mitochondrial DNA polymerase does not affect total dNTP pools in mouse embryos
  2020 DOI: 10.1101/2020.03.04.971283
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