Bappaditya Dey
National Inst of Animal Biotech (NIAB), National Institute of Animal Biotechnology, University of Delhi, Chaudhary Charan Singh Haryana Agricultural University, Boston University
About
Dr. Dey’s experience spans various aspects of research in Tuberculosis (TB) including, molecular basis of TB pathogenesis: host-pathogen interaction, immunology of TB and vaccine development and animal models of TB, TB latency and reactivation. He developed several genetically engineered recombinant vaccines, some of which imparted heightened protection among the experimental TB vaccines studied till date. His research on bacterial cyclic-di-nucleotide (CDN) second messengers signaling has led to the elucidation of novel network of Cytoplasmic Surveillance Pathway (CSP) activation that promise to stimulate considerable future research into the consequences of signal transduction interference by intracellular bacterial pathogens and also into novel therapies that may target this newly characterized virulence mechanism. At NIAB, Dr. Dey’s primary research interests are to understand the immune-genetic basis of resistance and susceptibility of different breeds of cattle to TB and other mycobacterial infections, to develop genetic diagnostics, recombinant live attenuated vaccines and engineered probiotic based preventive and therapeutic strategies against animal diseases with public health and economic importance.
Employment
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National Inst of Animal Biotech (NIAB) Scientist-F2024 - Present
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National Institute of Animal Biotechnology Scientist-E2017 - 2023
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Boston University Senior Research Scientist2016 - 2017
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Johns Hopkins University Postdoctoral Fellow2011 - 2016
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University of Delhi - South Campus Scientist-C (DBT project)2010 - 2011
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University of Delhi - South Campus Research Associate2009 - 2010
Education
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University of Delhi PhD2004 - 2010
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Chaudhary Charan Singh Haryana Agricultural University MVSc2002 - 2004
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West Bengal University of Animal and Fishery Sciences BVSc & AH1997 - 2002
Projects & Funding
Projects & funding information is unavailable.
Publications (31)
- Identifying a novel mechanism of L-leucine uptake in Mycobacterium tuberculosis using a chemical genomic approach Save
- Targeting Cyclic di-AMP Signaling through Diadenylate Cyclase Inhibition Reduces Methicillin Resistance in Clinical MRSA Isolates Save
- Targeting cyclic di-AMP signaling through diadenylate cyclase inhibition reduces methicillin resistance in clinical MRSA isolates Save
- Identifying a novel mechanism of L-leucine uptake in Mycobacterium tuberculosis using a chemical genomic approach Save
- Transcriptomic insights into Mycobacterium orygis infection-associated pulmonary granulomas reveal multicellular immune networks and tuberculosis biomarkers in cattle Save
- Multi-omics analysis uncovers differential growth kinetics of Japanese Encephalitis Virus in human and porcine macrophages Save
- Identifying a novel mechanism of L-leucine uptake in Mycobacterium tuberculosis using a chemical genomic approach Save
- Identifying a novel mechanism of L-leucine uptake in Mycobacterium tuberculosis using a chemical genomic approach Save
- A bovine pulmosphere model and multiomics reveal early host response signature in tuberculosis Save
- Transcriptomic profiling identifies breed-specific immune signatures of Tuberculosis susceptibility in cattle Save