0000-0003-2739-0056 About
My doctoral work involved designing and evaluating chitosan-based bioactive nanofibrous hemostats for emergency wound care. These materials exhibited hemostatic response times under 10 seconds in both in vitro and in vivo rat models. I performed full-spectrum pre-clinical evaluations, including arterial bleeding, liver puncture model, wound healing studies, toxicity assessments, immunogenicity, and clot mechanical integrity. These trials required survival surgeries and post-operative care, providing me with experience in animal handling, ethical compliance, and physiological monitoring in rodents and rabbits.
Beyond hemostats, I have contributed to projects including 3D bioprinting for testicular tissue engineering, bone tissue scaffolds in collaboration with ceramic engineering, physics department at NIT Rourkela, and the development of injectable nanofibril-based hydrogels as intramammary teat sealant for treating mastitis in dairy animals. I have worked with various biomaterials and possess strong hands-on expertise in molecular biology techniques, immunohistochemistry, and biomaterial characterization. This has resulted in over 11 peer-reviewed publications, including in the International Journal of Biological Macromolecules, Ceramics International, and the Journal of Biomaterials Science, which involve animal model-based experimentation.
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Publications (12)
- Structural, microstructural, dielectric, mechanical properties of PVDF/HAP nanocomposite films for bone regeneration applications Save
- Robust tissue adhesion in biomedical applications: enhancing polymer stability in an injectable protein-based hydrogel Save
- In vitro biocompatibility, electrical, mechanical, and structural study of lead-free HAp/BNBK composites for bio-implantation Save
- Analyzing the effect of heparin on in vitro capacitation and spermatozoal RNA population in goats Save
- Enhancing physicochemical, mechanical, and bioactive performances of monetite nanoparticles reinforced chitosan‐PEO electrospun scaffold for bone tissue engineering Save
- Tissue Engineering and Regenerative Medicine International Society Asia‐Pacific Chapter Conference 2022 Save
- Gelatin/monetite electrospun scaffolds to regenerate bone tissue: Fabrication, characterization, and in-vitro evaluation Save
- Microstructural, dielectric, mechanical, and biological properties of hydroxyapatite (HAp)/BZT-BCT (0.5Ba(Zr0.2Ti0.8)O3-0.5(Ba0.7Ca0.3)TiO3) bio-composites with improved mechano-electrical properties for bone repair Save
- Engineering Biomaterials for Testicular Tissue Engineering and In Vitro Spermatogenesis Save
- Fast acting hemostatic agent based on self-assembled hybrid nanofibers from chitosan and casein Save