MR

Muhammad Hamid Rashid

National Institute for Biotechnology and Genetic Engineering

Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Enzyme Production and Characterization · Enzyme Catalysis and Immobilization · Biofuel production and bioconversion

ORCID iD 0000-0003-2759-0533
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About

I am an experienced Deputy Chief scientist (DCS) at a renowned institute National institute for biotechnology and genetic engineering, Pakistan. I have completed his PhD from University of the Punjab, Lahore, Pakistan in 1998 and awarded with a post-Doc fellowship from Osaka Prefecture University, Japan in 2002-2004. I have been awarded with multiple national and international scientific achievements in his 32 years of career. My expertise includes improvement of enzyme properties through immobilization, carboxyl & amino group modification for thermostabilization and activation of enzymes, elucidation of kinetic mechanisms of activation/ inhibition of enzymes by metal ions, microbial strain development for the improvement in productivity and enzyme properties for application in industrial processes, growth kinetics, Up- & down-stream processing of enzymes, and kinetics and thermodynamics of stability & function of enzymes. I have been supervised 15 PhDs, 16 Mphil and 12 MSc graduates in her professional career. I am an author and co-author of 63 publications.

Employment

Education

Education history is unavailable.

Projects & Funding

  • Development of Super Koji for the Enhanced Production of Thermostable Food Grade Enzymes for Application in Food & Feed Industry Higher Education Commission, Pakistan
    2018 - 2021
  • Development of Magnetic Nanoparticles Based Support for the Immobilization of NIBGE--Amylases to Produce Maltose Syrup from Corn Starch Higher Education Commission, Pakistan
    2018 - 2021
  • Multi-copy Integration of Phytase Gene (phy-A) in Super Koji (Aspergillus oryzae) to Enhance the Production of Phytases Higher Education Commission, Pakistan
    2018 - 2019
  • “Enzymes Production by Super Koji (Aspergillus oryzae) for Food & Feed Industry: Process Scaling-Up at Pilot and Industrial Level” Higher Education Commission, Pakistan
    2017 - 2019

Publications (27)

  • Draft genome sequence of Streptomyces carpaticus FH1
    Microbiology Resource Announcements 2025 DOI: 10.1128/mra.01054-24
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  • Draft genome sequence of extracellular enzyme-producing Bacillus paralicheniformis strain NBG-07
    Microbiology Resource Announcements 2024 DOI: 10.1128/mra.00096-24
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  • Interaction of nanomaterials with microbes. In: Biodegradation and Biodeterioration at the Nanoscale
    2022
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  • Microbial Cellulases: A Review on Strain Development, Purification, Characterization and their Industrial Applications.
    2021
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  • Single step immobilization of CMCase within agarose gel matrix: Kinetics and thermodynamic studies.
    2021
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  • Design of heterostructured hybrids comprising ultrathin 2D bismuth tungstate nanosheets reinforced by chloramphenicol imprinted polymers used as biomimetic interfaces for mass-sensitive detection. Colloids and Surfaces B: Biointerfaces
    2020
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  • Gamma Rays Mediated Mutagenesis of Super Koji (Aspergillus oryzae) to enhance the Thermostability and Production of CMCases: Process Scale-up at Pilot Level
    2019 DOI: 10.21203/rs.2.10510/v1
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  • Current situation of biofuel production and its enhancement by CRISPR/Cas9-mediated genome engineering of microbial cells
    2019
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  • Enzyme Immobilization on Metal-Organic Framework (MOF): Effects on Thermosability and Function
    2019
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  • Flavonol biosynthesis by non heme iron dioxygenases: A computational study into the structure and mechanism
    2019
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  • Purification and Extreme Thermostabilization of Glucoamylase by Zinc Produce of Novel Fungus Gymnoascella citrina.
    2019
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  • Random mutagenesis of super Koji (Aspergillus oryzae): improvement in production and thermal stability of α-amylases for maltose syrup production
    BMC Microbiology 2018 DOI: 10.1186/s12866-018-1345-y
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  • Effect of metal Ions on kinetics and thermostability of α-amylase isolated from Aspergillus oryzae
    2018
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  • Random Mutagenesis of Super Koji (Aspergillus oryzae): Improvement in Production and Thermal Stability of α-Amylases for Maltose Syrup Production
    2018
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  • Cost efficient entrapment of β-glucosidase in nanoscale latex and silicone polymeric thin films for use as stable biocatalysts
    2016
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  • Effect of Mg2+ and Al3+ ions on thermodynamic and physiochemical properties of Aspergillus niger invertases
    2015
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  • Microbial invertases: A review on kinetics, thermodynamics, physiochemical properties
    Process Biochemistry 2015
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  • Gamma ray mediated mutagenesis of Phialocephala humicola: effect on kinetics and thermodynamics of a-amylase production
    African Journal of Microbiology Research 2012
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  • Physiochemical properties and kinetics of glucoamylase produced from deoxy-D-glucose resistant mutant of Aspergillus niger for soluble starch hydrolysis
    Food chemistry 2012
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  • Carboxyl group modification of Gymnoascella citrina glucoamylase: Cross-linking with hydrophobic nucleophile enhanced thermostability and thermophilicity
    Clinical Biochemistry 2011
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