Priyanka G Bhosale

About

I am currently based at the UCL Cancer Institute as an ACED Pathway Fellow, supported by a CRUK grant focused on the early detection of oral premalignant lesions and head and neck squamous cell carcinomas (HNSCs). I completed my postdoctoral research in Professor Fiona Watt’s lab at King’s College London in January 2025.
My research investigates how acquired mutations alter cellular mechanisms and affect the biology of oral cancers. I am particularly interested in exploring the genomic, phenotypic, and metabolic differences that contribute to tumorigenesis.
Broadly, my areas of expertise include HNSC, oral premalignant lesions, oral histopathology, mitochondrial metabolism, epithelial stem cell biology, immuno-oncology, multi-omic analyses (genomics, transcriptomics, metabolomics), and both mouse and cell-based models.

Employment

• University College London ACED Pathway Fellow (CRUK Award)
  2025 - Present
• King's College London Postdoctoral Research Associate
  2018 - 2025
• University of Bristol Postdoctoral research associate
  2017 - 2018
• Advanced Centre for Treatment Research and Education in Cancer PhD Fellow
  2009 - 2017
• Bangalore Biotech Labs PVT LTD (Biozeen) BCIL (Biotech Consortium India Limited) Fellow
  2008 - 2009

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (10)

• Neutral evolution of snoRNA Host Gene long non-coding RNA affects cell fate control
  The EMBO Journal 2024 DOI: 10.1038/s44318-024-00172-8
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• Myc-dependent dedifferentiation of Gata6+ epidermal cells resembles reversal of terminal differentiation.
  Nature cell biology 2023 DOI: 10.1038/s41556-023-01234-5
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• Caspase activation in tumour-infiltrating lymphocytes is associated with lymph node metastasis in oral squamous cell carcinoma.
  The Journal of pathology 2023 DOI: 10.1002/path.6145
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• Genome-wide DNA methylation profiling of HPV-negative leukoplakia and gingivobuccal complex cancers.
  Clinical epigenetics 2023 DOI: 10.1186/s13148-023-01510-z
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• NOTCH1 signaling in oral squamous cell carcinoma via a TEL2/SERPINE1 axis.
  Oncotarget 2019 DOI: 10.18632/oncotarget.27306
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• Detection of HPV E6/E7 mRNA in Clinical Samples Using RNA In Situ Hybridization.
  Methods in molecular biology (Clifton, N.J.) 2018 DOI: 10.1007/978-1-4939-7565-5_15
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• Recurring Amplification at 11q22.1-q22.2 Locus Plays an Important Role in Lymph Node Metastasis and Radioresistance in OSCC.
  Scientific reports 2017 DOI: 10.1038/s41598-017-16247-y
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• Chromosomal Alterations and Gene Expression Changes Associated with the Progression of Leukoplakia to Advanced Gingivobuccal Cancer.
  Translational oncology 2017 DOI: 10.1016/j.tranon.2017.03.008
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• Low prevalence of transcriptionally active human papilloma virus in Indian patients with HNSCC and leukoplakia.
  Oral surgery, oral medicine, oral pathology and oral radiology 2016 DOI: 10.1016/j.oooo.2016.06.006
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• Downregulation of keratin 76 expression during oral carcinogenesis of human, hamster and mouse.
  PloS one 2013 DOI: 10.1371/journal.pone.0070688
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