Naga Leelaram Majety

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Publications (10)

• Inhibition of DNA cleavage and strand passage activities of Mycobacterium tuberculosis topoisomerase I
  Nucleic Acids Research 2025 DOI: 10.1093/nar/gkaf929
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• Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation
  Science 2020 DOI: 10.1126/science.abc3753
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• Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation
  Cell 2017 DOI: 10.1016/j.cell.2017.07.011
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• Carboxyl terminal domain basic amino acids of mycobacterial topoisomerase I bind DNA to promote strand passage
  Nucleic Acids Research 2013 DOI: 10.1093/nar/gkt506
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• Type IA topoisomerase inhibition by clamp closure
  The FASEB Journal 2013 DOI: 10.1096/fj.12-226118
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• Characterization of DNA topoisomerase I from Mycobacterium tuberculosis: DNA cleavage and religation properties and inhibition of its activity
  Archives of Biochemistry and Biophysics 2012 DOI: 10.1016/j.abb.2012.10.004
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• Inhibition of type IA topoisomerase by a monoclonal antibody through perturbation of DNA cleavage-religation equilibrium
  FEBS Journal 2012 DOI: 10.1111/j.1742-4658.2011.08398.x
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• A new ELISA plate based microtiter well assay for mycobacterial topoisomerase I for the direct screening of enzyme inhibitory monoclonal antibody supernatants
  Journal of Immunological Methods 2010 DOI: 10.1016/j.jim.2010.03.008
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• Deciphering the Distinct Role for the Metal Coordination Motif in the Catalytic Activity of Mycobacterium smegmatis Topoisomerase I
  Journal of Molecular Biology 2009 DOI: 10.1016/j.jmb.2009.08.064
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• Immunological cross-reactivity of mycobacterial topoisomerase I and divergence from other bacteria
  Tuberculosis 2009 DOI: 10.1016/j.tube.2009.05.004
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