Dineshbabu Takkella
University of Kansas, IIT Kharagpur, Indian Institute of Technology Hyderabad, Andhra University, Krishna University
About
I am a Postdoctoral Researcher at the University of Kansas, studying the structure, dynamics, and function of non-coding RNA elements in the Hepatitis C virus (HCV) genome. My current research combines single-molecule fluorescence techniques, including smFRET, FCS, and FLIM, with biochemical approaches to investigate RNA conformational dynamics and molecular interactions involved in viral regulation.
Previously, my Ph.D. research in Biophysical Chemistry at the Indian Institute of Technology Hyderabad focused on the structure, dynamics, and interactions of DNA and proteins in biomimetic environments. I investigated DNA methylation, DNA-Protein, DNA-drug and protein-drug interactions, liquid-liquid phase separation, micellar systems, and supramolecular assemblies.
My broader interests include RNA/DNA biophysics, biomolecular dynamics, single-molecule spectroscopy, molecular recognition, and fluorescence-based structural biology.
Employment
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University of Kansas Postdoctoral Researcher2026 - Present
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IIT Kharagpur Postdoctoral Researcher2026 - 2026
Education
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Indian Institute of Technology Hyderabad Doctor of Philosophy (Ph.D.)2020 - 2025
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Andhra University Master of Science (M.Sc.)2016 - 2018
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Krishna University B.Sc. (Chemistry)2013 - 2016
Projects & Funding
Projects & funding information is unavailable.
Publications (25)
- Biophysical aspects of 3-Hydroxychromone-based uracil's interaction with the serum protein Save
- Photophysical tuning of fluorinated benzimidazole fluorophores: Donor-acceptor systems and BSA interactions Save
- Surface-controlled PET in corrole-graphene hybrid composites Save
- Unraveling the mechanism of graphene oxide-mediated disruption of protein dimers Save
- Structural and Energetic Analysis of Lenacapavir Binding to Human Serum Albumin: A Computational Study Using Docking, Molecular Dynamics, and MMPBSA/MMGBSA Save
- New insights into the structure and dynamics of the epigenetic modifications on DNA Save
- Coumarin 153, a solvatochromic fluorescent probe, for analyzing the biodiesel blends derived from various feedstocks Save
- Carbazole-rhodanine conjugate acts as an effective fluorescence biomarker for protein structural dynamics studies Save
- Bile salt induced aggregation and nanostructure formation of β-lactoglobulin in gastrointestinal environments Save
- Influence of Bovine Liver Catalase on Self-Assembled Structures of a Surface-Active Ionic Liquid Save