PM
Prabu Manoharan
Madurai Kamaraj University, Indian Institute of Chemical Biology CSIR, Bharathidasan University
0000-0003-2945-9694
Employment
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Madurai Kamaraj University Postdoctoral Researcher2017 - Present
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Madurai Kamaraj University Postdoctoral Researcher2014 - 2017
Education
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Indian Institute of Chemical Biology CSIR Ph.D in Biophysics, Molecular Biology and Genetics2008 - 2014
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Bharathidasan University M.Sc Bioinformatics2005 - 2007
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Madurai Kamaraj University B.Sc Botany Splz in Industrial Microbiology2002 - 2005
Projects & Funding
Projects & funding information is unavailable.
Publications (13)
- Fragment-based virtual screening approach and molecular dynamics simulation studies for identification of BACE1 inhibitor leads Save
- Stigmatellin Y - An anti-biofilm compound from Bacillus subtilis BR4 possibly interferes in PQS-PqsR mediated quorum sensing system in Pseudomonas aeruginosa. Save
- Computational analysis of BACE1-ligand complex crystal structures and linear discriminant analysis for identification of BACE1 inhibitors with anti P-glycoprotein binding property. Save
- Computational profiling of pore properties of outer membrane proteins. Save
- Target specific proteochemometric model development for BACE1 - protein flexibility and structural water are critical in virtual screening. Save
- Neutralization function affected by single amino acid replacement in the HIV-1 antibody targets. Save
- Modeling the closed and open state conformations of the GABA(A) ion channel--plausible structural insights for channel gating. Save
- Rationalizing lead optimization by consensus 2D- CoMFA CoMSIA GRIND (3D) QSAR guided fragment hopping in search of γ-secretase inhibitors. Save
- Discovery of safe and orally effective 4-aminoquinaldine analogues as apoptotic inducers with activity against experimental visceral leishmaniasis. Save
- Rationalizing fragment based drug discovery for BACE1: insights from FB-QSAR, FB-QSSR, multi objective (MO-QSPR) and MIF studies. Save