Amit Chouhan
University of St Andrews, Baylor College of Medicine, University of Texas Southwestern Medical Center Dallas / UT Arlington, University of Texas Health Science Center at San Antonio
0000-0003-2991-6402
About
A qualified electrical engineer who is trained as a neuroscientist and has developed efficient human iPSC and Drosophila models of neurological disorders for genetic & drug screening. I am currently undertaking a PhD, co-supervised by Prof Siddharthan Chandran (University of Edinburgh) & Dr. Gareth Miles (Reader, University of St Andrews), investigating motoneuron-astrocyte crosstalk, and deciphering mechanisms underlying the dysfunction of motoneurons derived from ALS patient iPSCs. I am an expert on electrophysiology and calcium imaging techniques and utilize them to develop high throughout drug screening assays. As part of NC3Rs funded CRACK IT challenge, I am involved with characterization of human dorsal root ganglion neurons derived from human organ donors.
Employment
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University of St Andrews Post Graduate Researcher2015 - Present
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Baylor College of Medicine Research Associate2012 - 2014
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University of Texas Health Science Center at San Antonio Research Associate2008 - 2012
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University of Texas Health Science Center at San Antonio Senior Research Assistant2007 - 2008
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Texas Scottish Rite Hospital for Children Research Assitant2006 - 2006
Education
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University of St Andrews PhD Neuroscience2015 - Present
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University of Texas Southwestern Medical Center Dallas / UT Arlington Master of Science2004 - 2006
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National Institute of Technology Raipur Department of Electrical Engineering Bachelor of Engineering1999 - 2003
Projects & Funding
Projects & funding information is unavailable.
Publications (9)
- Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing Save
- High-Probability Neurotransmitter Release Sites Represent an Energy-Efficient Design Save
- Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease Save
- The redistribution of Drosophila vesicular monoamine transporter mutants from synaptic vesicles to large dense-core vesicles impairs amine-dependent behaviors Save
- Genetically encoded pH-indicators reveal activity-dependent cytosolic acidification of Drosophila motor nerve termini in vivo Save
- Cytosolic Calcium Coordinates Mitochondrial Energy Metabolism with Presynaptic Activity Save
- Differential control of presynaptic CaMKII activation and translocation to active zones Save
- Modality-specific axonal regeneration: Toward selective regenerative neural interfaces Save
- Presynaptic mitochondria in functionally different motor neurons exhibit similar affinities for Ca2+ but exert little influence as Ca 2+ buffers at nerve firing rates in situ Save