Honghuang Lin
University of Massachusetts Chan Medical School, Boston University School of Medicine, National University of Singapore, Peking University, Dana-Farber Cancer Institute
Research areas: Biochemistry, Genetics and Molecular Biology · Genetics · Genetic Associations and Epidemiology · Dementia and Cognitive Impairment Research · Cardiac electrophysiology and arrhythmias
0000-0003-3043-3942
About
The advance of high-throughput technologies such as microarray and next generation sequencing offers a great opportunity to study biological systems through genome-wide approach. My research focuses on the design of statistical and computational tools to identify genetic or epigenetic causes of medically important diseases. In particular, I am interested in the discovery of various pathogenesis-related variations, such as single nucleotide polymorphisms (SNPs), copy number variations (CNVs), insertions/deletions, and methylation.
Employment
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UMass Medical School Professor2022 - Present
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Boston University School of Medicine Associate Professor2019 - 2021
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Boston University School of Medicine Assistant Professor2010 - 2019
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Dana Farber Cancer Institute Postdoctoral Fellow/Bioinformatics Analyst2007 - 2010
Education
- 2003 - 2007
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Peking University Bachelor of Science1999 - 2003
Projects & Funding
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Futurizing Brain Health Monitoring Platform American Heart Association2020 - 2024
Publications (220)
- Practice Effects on Repeated Self-Administered Digital Cognitive Assessments in Cognitively Intact Older Adults from the Framingham Heart Study: Longitudinal Observational Study Save
- Introduction to using symbolic regression for interpretable machine learning in healthcare Save
- Associations Between Smartwatch‐Derived Measures and Cognitive Function: Findings From the Electronic Framingham Heart Study Save
- Cross-cohort analysis of expression and splicing quantitative trait loci in TOPMed Save
- Dynamic Risk Trajectories for Sudden Cardiac Arrest: The Role of Recurrent Cardiovascular Events Save
- Genetic Determinants of Pulmonary Artery Size in over 50,000 Subjects with and without COPD Save
- Leveraging routine clinical data for dementia risk prediction using machine learning Save
- Exploring Sleep Measures for Longitudinal Home Monitoring and Cross-Device Comparability Under Real-World Asynchronous Deployment in an Aging Cohort: Longitudinal Observational Study (Preprint) Save
- Expert Clinical Interpretation of Continuous Glucose Monitor Reports From Individuals Without Diabetes Save
- Digital Stroop Test as a neurocognitive marker in a community-based sample of older adults: Data from the Framingham Heart Study Save
- Associations Between Smartphone-Based Finger Tapping and Cognitive Performance in Older Adults: Observational Study Save
- Early prediction of Alzheimer’s disease using longitudinal electronic health records of US military veterans Save
- Duration of contact sports play associated with aberrant DNA methylation in human frontal cortex Save
- How Life-Course Trajectories of Physical Activity Track With Cognitive Decline Save
- Longitudinal Clinical Note–Derived Signals Are Consistent Across Healthcare Systems And Support Alzheimer’s Disease Risk Prediction Save
- MealRes-Gate: Forecasting Glucose Dynamics from CGM and Sparse Meal Logs Using Residual-Gated Multimodal Transformer Save
- Duration of contact sports play associated with aberrant DNA methylation in human frontal cortex Save
- Digital Neuropsychological Measures in Older Adults Exposed to Repetitive Head Impacts Save
- Exploring the Effect of Repetitive Head Impacts on the Stability of Digital Cognitive Measures in Cognitively Intact Older Adults: A Pilot Study Save
- Gene‐based association study of rare structural variants in Alzheimer's Disease Save