FA
Fawaz Alzaid
Dasman Diabetes Institute, Inserm, King's College London, University of Westminster
Research areas: Medicine · Endocrinology, Diabetes and Metabolism · Adipokines, Inflammation, and Metabolic Diseases · Adipose Tissue and Metabolism · Liver Disease Diagnosis and Treatment
0000-0003-3056-3640
About
Research associate investigating metabolic regulation of inflammation. Current projects target cellular bioenergetics of innate immunity and predictive immunophenotyping of patients with diabetes, its complications and comorbidities. My research highlights include publications in Nature Medicine, Nature Communications, Cell Reports and JCI Insight deciphering mechanisms of tissue inflammation in diabetes.
Employment
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Dasman Diabetes Institute Senior Scientist2022 - Present
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INSERM Research Associate - Group Leader2017 - Present
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INSERM Post-doctoral fellow2014 - 2017
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University of Westminster Post-doctoral fellowship2012 - 2014
Education
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King's College London PhD in Nutritional Sciences2008 - 2012
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University of Westminster MSc/MPH Nutrition, Physical Activity and Public Health2007 - 2008
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University of Westminster BSc (Hons) Nutrition2003 - 2007
Projects & Funding
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Allocation Exceptionelle Société Francophone du Diabète2021 - 2023
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Monocyte metabolism and bioenergetic responses in type 2 diabetes and cardiovascular disease European Foundation for the Study of Diabetes2020 - 2023
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Mitochondrial bioenergetics of metabolic inflammation: Derepressing mitochondrial respiration as a novel therapeutic approach in type-2 diabetes – MitoFLAME National Agency for Research2019 - 2023
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Targeting PUFA metabolism in MAcrophages In cardiovascular diseases – PUMAs National Agency for Research2019 - 2022
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INSERM-Industry Open Innovation Institut National de la Santé et de la Recherche Médicale2018 - 2021
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Young investigator award Institut National de la Santé et de la Recherche Médicale2018 - 2019
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Interferon signalling and macrophage mitochondrial adaptation ITMO-PMN (INSERM)2018 - 2019
Publications (82)
- Metabolic inflammation, obesity, and cancer Save
- What Is a Clinically Meaningful Change in Diabetes Distress? Findings for Diabetes Care and Research From the SFDT1 Cohort Save
- Global challenges in diabetes research and care: which way forward? An appraisal from the EASD Global Council Save
- Immune cell–adipose tissue crosstalk in metabolic diseases with a focus on type 1 diabetes Save
- Measurement of serum 1,5-AG provides insights for diabetes management and the anti-viral immune response Save
- Biotics and Bacterial Function: Impact on Gut and Host Health Save
- IL-1β-Induced CXCL10 Expression in THP-1 Monocytic Cells Involves the JNK/c-Jun and NF-κB-Mediated Signaling Save
- Gut Dysbiosis Shaped by Cocoa Butter-Based Sucrose-Free HFD Leads to Steatohepatitis, and Insulin Resistance in Mice Save
- Blood Monocyte Phenotype Is A Marker of Cardiovascular Risk in Type 2 Diabetes Save
- Comparative efficacy, toxicity, and insulin-suppressive effects of simvastatin and pravastatin in fatty acid-challenged mouse insulinoma MIN6 β-cell model Save
- Editorial: Neuroinflammation, neurodegeneration and metabolic disease: from molecular mechanisms to therapeutic innovation Save
- Glucose intolerance induces anxiety-like behaviors independent of obesity and insulin resistance in a novel model of nutritional metabolic stress Save
- High glycaemic variability in individuals with type 1 diabetes is associated with a reduced proportion of CD8+ TNF+ cells in response to influenza A virus Save
- High glycemic variability is associated with a reduced T cell cytokine response to influenza A virus Save
- Neutral Sphingomyelinase 2 Inhibition Limits Hepatic Steatosis and Inflammation Save
- PPARdelta: A key modulator in the pathogenesis of diabetes mellitus and Mycobacterium tuberculosis co-morbidity Save
- Soybean oil-based HFD induces gut dysbiosis that leads to steatosis, hepatic inflammation and insulin resistance in mice Save
- The effect of automated insulin delivery system use on diabetes distress in people with type 1 diabetes and their caregivers: A systematic review and meta-analysis Save
- Unraveling Verapamil’s Multidimensional Role in Diabetes Therapy: From β-Cell Regeneration to Cholecystokinin Induction in Zebrafish and MIN6 Cell-Line Models Save
- Genetic variants of interferon-response factor 5 are associated with the incidence of chronic kidney disease: the D.E.S.I.R. study Save