Neal Bennett

Employment

Employment history is unavailable.

Education

Education history is unavailable.

Projects & Funding

• Metabolic Vulnerability and Effects of APOE in Human Neurons with Impaired Endocytic Recycling National Institute on Aging
  2022 - 2027
• Bioenergetic and Proteolytic Impact of Ubiquitin-like Pathways in Metabolically Stressed Neurons National Institute on Aging
  2019 - 2022

Publications (22)

• Metabolomic, lipidomic, and N-glycomic analyses of a human cell model of Krabbe disease reveal treatable deficits in glycosylation and serine-ceramide metabolism
  2026 DOI: 10.64898/2026.08.12.744295
  +Save
• Genetic Regulators of Neuronal Survival Across Metabolic States
  2026 DOI: 10.6084/m9.figshare.32305263
  +Save
• Genome-Wide CRISPRi Survival Screen Phenotypes and Statistics of Neuronal Survival Across Metabolic States
  2026 DOI: 10.6084/m9.figshare.32305266
  +Save
• Genome-wide CRISPRi screen identifies basigin loss as protective in cardiac hypoxia
  2026 DOI: 10.64898/2026.01.26.701810
  +Save
• Genetic regulators of neuronal survival across metabolic environments
  2025 DOI: 10.64898/2025.12.19.695350
  +Save
• Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production
  Proceedings of the National Academy of Sciences 2024 DOI: 10.1073/pnas.2307904121
  +Save
• Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production
  2023 DOI: 10.1101/2023.10.14.562276
  +Save
• Biallelic pathogenic variants in COX11 are associated with an infantile‐onset mitochondrial encephalopathy
  Rocío Rius, Neal K. Bennett, Kaustuv Bhattacharya +13 more
  Human Mutation 2022 DOI: 10.1002/humu.24453
  +Save
• Primary and metastatic tumors exhibit systems-level differences in dependence on mitochondrial respiratory function.
  PLoS biology 2022 DOI: 10.1371/journal.pbio.3001753
  +Save
• Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain.
  Cell 2022 DOI: 10.1016/j.cell.2022.09.004
  +Save
• Defining the ATPome reveals cross-optimization of metabolic pathways.
  Nature communications 2020 DOI: 10.1038/s41467-020-18084-6
  +Save
• A high-throughput screen of real-time ATP levels in individual cells reveals mechanisms of energy failure.
  PLoS biology 2018 DOI: 10.1371/journal.pbio.2004624
  +Save
• Mapping the Genetic Landscape of Human Cells.
  Cell 2018 DOI: 10.1016/j.cell.2018.06.010
  +Save
• Optical High Content Nanoscopy of Epigenetic Marks Decodes Phenotypic Divergence in Stem Cells.
  Scientific reports 2017 DOI: 10.1038/srep39406
  +Save
• Polymer brain-nanotherapeutics for multipronged inhibition of microglial α-synuclein aggregation, activation, and neurotoxicity.
  Biomaterials 2016 DOI: 10.1016/j.biomaterials.2016.10.001
  +Save
• Self-Assembling Peptide Nanofiber Scaffolds for 3-D Reprogramming and Transplantation of Human Pluripotent Stem Cell-Derived Neurons.
  ACS biomaterials science & engineering 2016 DOI: 10.1021/acsbiomaterials.6b00156
  +Save
• Convergence of Highly Resolved and Rapid Screening Platforms with Dynamically Engineered, Cell Phenotype-Prescriptive Biomaterials.
  Current pharmacology reports 2016 DOI: 10.1007/s40495-016-0057-y
  +Save
• Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds
  Nature Communications 2016 DOI: 10.1038/ncomms10862
  +Save
• α-Synuclein pre-formed fibrils impair tight junction protein expression without affecting cerebral endothelial cell function
  Experimental Neurology 2016 DOI: 10.1016/j.expneurol.2016.09.003
  +Save
• Carbon Nanotube Composites as Multifunctional Substrates for In Situ Actuation of Differentiation of Human Neural Stem Cells
  Advanced Healthcare Materials 2014 DOI: 10.1002/adhm.201400042
  +Save