Kannan Gunasekaran

Employment

• Nutcracker Therapeutics Senior Vice President
  2021 - Present

Education

• Nutcracker Therapeutics Ph.D.
  1993 - 1999

Projects & Funding

Projects & funding information is unavailable.

Publications (53)

• Discovery of a Peptoid-Based Nanoparticle Platform for Therapeutic mRNA Delivery via Diverse Library Clustering and Structural Parametrization
  2024
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• 1359 NTX-0471, engineered multivalent SIRPa and bispecific SIRPa-antiCCR4 molecules demonstrate superior activity providing path for mRNA expressedin-vivobiologics
  2023
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• Molecular architecture determines brain delivery of a transferrin receptor-targeted lysosomal enzyme.
  2022
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• Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic
  2021
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• Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
  2021
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• Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice.
  2020
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• High-Throughput Liquid Chromatography-Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II.
  2020
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• High-Throughput Liquid Chromatography–Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II
  2020
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• Novel FACS based method demonstrates CNS cell-type distribution and efficacy of a BBB penetrant ERT in a mouse model of MPS II
  2020
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• Engineering Antibody Reactivity for Efficient Derivatization to Generate Na V 1.7 Inhibitory GpTx-1 Peptide–Antibody Conjugates
  2017
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