CHUN YIP CHAN

Employment

• Skin Research Institute of Singapore
  2018 - Present
• National University of Singapore
  2015 - 2018

Education

• National University of Singapore Doctor of Philosophy (Pharmaceutical Science)
  2011 - 2015
• National University of Singapore Bachelor of Science (Pharmacy), 1st Class Hons
  2007 - 2011

Projects & Funding

Projects & funding information is unavailable.

Publications (14)

• Determinants of exposures to preconception plasma perfluoroalkyl substances and periconceptional urinary phthalate and pesticide metabolites in a Singaporean longitudinal preconception cohort
  Environmental Research 2026 DOI: 10.1016/j.envres.2026.125079
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• Combination amino acids and glucose effects on insulin and GLP-1 secretion
  Biochemical Journal 2026 DOI: 10.1042/BCJ20253316
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• Mechanistic Middle-Out Physiologically Based Toxicokinetic Modeling of Transporter-Dependent Disposition of Perfluorooctanoic Acid in Humans
  Environmental Science & Technology 2023 DOI: 10.1021/acs.est.2c05642
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• A compromised developmental trajectory of the infant gut microbiome and metabolome in atopic eczema
  Le Duc Huy Ta, James Chun Yip Chan, Gaik Chin Yap +25 more
  Gut Microbes 2020 DOI: 10.1080/19490976.2020.1801964
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• Physiologically-Based Pharmacokinetic Modeling to Predict the Clinical Efficacy of the Coadministration of Lopinavir and Ritonavir against SARS-CoV-2.
  Clinical pharmacology and therapeutics 2020 DOI: 10.1002/cpt.2014
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• Increased Protein S-Glutathionylation in Leber's Hereditary Optic Neuropathy (LHON).
  International journal of molecular sciences 2020 DOI: 10.3390/ijms21083027
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• Bottom-up physiologically-based biokinetic modelling as an alternative to animal testing
  ALTEX 2019 DOI: 10.14573/altex.1812051
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• Reactive Metabolite-induced Protein Glutathionylation: a Potentially Novel Mechanism Underlying Acetaminophen Hepatotoxicity
  Molecular & Cellular Proteomics 2018 DOI: 10.1074/mcp.ra118.000875
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• In Silico and in Vitro Interactions between Short Chain Fatty Acids and Human Histone Deacetylases
  Biochemistry 2017 DOI: 10.1021/acs.biochem.7b00508
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• A novel LCMSMS method for quantitative measurement of short-chain fatty acids in human stool derivatized with 12C- and 13C-labelled aniline.
  Journal of pharmaceutical and biomedical analysis 2017 DOI: 10.1016/j.jpba.2017.01.044
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• Synergistic disruption of ERα/HER2 crosstalk by endoxifen and lapatinib in breast cancer cells
  Cancer Chemotherapy and Pharmacology 2016 DOI: 10.1007/s00280-016-3211-7
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• The Isotope-Coded Affinity Tag Method for Quantitative Protein Profile Comparison and Relative Quantitation of Cysteine Redox Modifications
  Current Protocols in Protein Science 2015 DOI: 10.1002/0471140864.ps2302s82
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• Mechanism-based inactivation of CYP450 enzymes: a case study of lapatinib
  Drug Metabolism Reviews 2015 DOI: 10.3109/03602532.2014.1003648
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• Reversible time-dependent inhibition of cytochrome P450 enzymes by duloxetine and inertness of its thiophene ring towards bioactivation
  Toxicology Letters 2011 DOI: 10.1016/j.toxlet.2011.07.019
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