Ajay Pratap Singh
University of Mississippi Medical Center, University of South Alabama, Devi Ahilya University, Aligarh Muslim University, University of South Alabama Mitchell Cancer Institute
0000-0003-3492-6330
About
I have several years of experience of working in the area of cancer biology. Specifically, my research during these past years has remained focused on understanding the role of deregulated genes in pancreatic and prostate cancers, dissecting their regulatory pathways, and exploiting their clinical potential in diagnosis, prognosis and therapy. I am specifically interested in understanding how the tumor cells respond to various cues in their surroundings, and how such interactions relate to tumor progression, metastasis and chemoresistance. A major focus is on characterizing the molecular mechanisms and signaling pathways involved in aggressive and drug-resistant nature of tumor cells and examining if those can be targeted for therapeutic interventions.
Employment
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University of Mississippi Medical Center Professor2024 - Present
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University of Mississippi Medical Center Associate Director of Basic and Translational Research2024 - Present
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University of South Alabama Professor and Director of Research2019 - 2024
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University of South Alabama Mitchell Cancer Institute Professor2016 - 2024
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University of South Alabama Program Leader, Cancer Biology2016 - 2024
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University of South Alabama Associate Professor2014 - 2016
Education
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Devi Ahilya University Doctor of Philosophy1996 - 2002
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Aligarh Muslim University Master of Science1992 - 1994
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Aligarh Muslim University Bachelor of Science (Honours)1988 - 1992
Projects & Funding
Projects & funding information is unavailable.
Publications (147)
- Cover Image: Volume 86 Issue 7 Save
- Smoking Behavior Is Associated With an Altered Immune Landscape in Prostate Cancer: Implications for Patient Outcomes Save
- Ataxia Telangiectasia Mutated (ATM) gene alterations as biomarkers of response to immune checkpoint inhibitors. Save
- MYB/AKT3 axis is a key driver of ovarian cancer growth, aggressiveness, and chemoresistance. Save
- Subtype- and race-specific variations in the immune landscape of breast cancer: therapeutic implications. Save
- MYB and HIF1α crosstalk drives hypoxia-induced transcriptional reprogramming and adaptive signaling alterations in pancreatic cancer. Save
- Nanomedicine in Cancer Therapeutics: Current Perspectives from Bench to Bedside. Save
- Cortisol affects macrophage polarization by inducing miR-143/145 cluster to reprogram glucose metabolism and by promoting TCA cycle anaplerosis. Save
- Obesity and Early-Onset Breast Cancer and Specific Molecular Subtype Diagnosis in Black and White Women: NIMHD Social Epigenomics Program. Save
- Prostate Cancer: Insights into Disease Progression and Therapeutic Challenges. Save