Manju A. Kurian or MA Kurian
University College London, Great Ormond Street Hospital, University College, London
About
Professor Manju Kurian is a Professor of Neurogenetics at UCL-Great Ormond Street Institute of Child Health. She is also a Consultant Paediatric Neurologist at Great Ormond Street Hospital. After graduating from Cambridge University, she trained in Paediatrics before subspecialising in Paediatric Neurology. At the end of her clinical training, she undertook a PhD (University of Birmingham) investigating the molecular genetic basis of childhood neurological disorders (2007-2011). She moved to UCL after her PhD, and is now an independent Principal Investigator at the Institute of Child Health. She has been awarded a Wellcome Intermediate Fellowship (2012-2017), L’Oreal For Women in Science Award (2017), NIHR Professorship (2017-2022), ICNA Jon Stobo Award (2018) and the The Jules Thorn Award for Biomedical Research (2019-2026). Her grant income exceeds £10 million and she has >200 peer reviewed publications including works in Nature Genetics, Science, Science Translational Medicine and Lancet Neurology.
Her current research encompasses gene discovery for childhood neurological disorders, including early onset neurodegeneration and movement disorders. Her lab uses mainly cell models to investigate the underlying pathological basis of disease. She works closely with UCL Gene Therapy groups to develop novel therapeutic strategies for children with pharmacoresistant movement disorders. Her long-term goal is to translate her research for patient benefit, through improved clinical diagnosis and precision medicine approaches.
Employment
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University College, London NIHR Research Professor2017 - 2023
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University College, London Wellcome Intermediate Fellow2013 - 2017
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University College London Professor of Neurogenetics2011 - Present
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Great Ormond Street Hospital Consultant Paediatric Neurologist2011 - Present
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University College, London GOSH Charity Clinician-Scientist2011 - 2013
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University of Birmingham Action Medical Research Training Fellow (PhD)2007 - 2011
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Birmingham Children's Hospital NTN Specialist Registrar2005 - 2006
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (235)
- Molecular and clinical spectrum of epilepsy-dyskinesia syndromes: a cross-sectional study of 609 patients. Save
- Deep Brain Stimulation for VPS16-Related Dystonia: A Multicenter Study. Save
- Development and Preliminary Validation of a Parkinsonism-Dystonia Scale for Infants and Young Children. Save
- Prenatal sodium channel dysfunction in Dravet syndrome alters cortical development Save
- Consensus Clinical Management Guideline for PLA2G6-Associated Neurodegeneration (PLAN). Save
- Genetic testing in cerebral palsy with clinical and neuroimaging variables. Save
- Genetic therapies for movement disorders - current status. Save
- Generation of an induced pluripotent stem cell line (UCLi026-A) from a patient with ADCY5-related disease carrying the heterozygous variant c.1253G > A; (p. Arg418Gln). Save
- Aromatic L-Amino Acid Decarboxylase Deficiency Save
- Imaging readiness in the gene therapy era-exploring standardized protocols for response assessment. Save