Irene Saha

Employment

• University of Arizona Researcher/Scientist III
  2025 - Present
• Cincinnati Children's Hospital Medical Center Research Fellow
  2019 - 2025

Education

• Cincinnati Children's Hospital Medical Center Postdoctoral Fellow
  2019 - Present

Projects & Funding

Projects & funding information is unavailable.

Publications (8)

• Alloreactive memory CD4 T cells promote transplant rejection by engaging DCs to induce innate inflammation and CD8 T cell priming.
  Irene Saha, Amanpreet Singh Chawla, Ana Paula B N Oliveira +7 more
  Proceedings of the National Academy of Sciences of the United States of America 2024 DOI: 10.1073/pnas.2401658121
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• Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells.
  Cell reports 2023 DOI: 10.1016/j.celrep.2023.113180
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• IEC-intrinsic IL-1R signaling holds dual roles in regulating intestinal homeostasis and inflammation.
  The Journal of experimental medicine 2023 DOI: 10.1084/jem.20212523
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• Effector memory CD4+ T cells induce damaging innate inflammation and autoimmune pathology by engaging CD40 and TNFR on myeloid cells.
  Science immunology 2022 DOI: 10.1126/sciimmunol.abk0182
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• IRF8 and BATF3 interaction enhances the cDC1 specific Pfkfb3 gene expression.
  Cellular immunology 2021 DOI: 10.1016/j.cellimm.2021.104468
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• IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility.
  Cell reports 2021 DOI: 10.1016/j.celrep.2021.108891
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• RelB suppresses type I Interferon signaling in dendritic cells
  Irene Saha, Hemant Jaiswal, Richa Mishra +9 more
  Cellular Immunology 2020 DOI: 10.1016/j.cellimm.2020.104043
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• Essential role of HCMV deubiquitinase in promoting oncogenesis by targeting anti-viral innate immune signaling pathways
  Puja Kumari, Irene Saha, Athira Narayanan +5 more
  Cell Death & Disease 2017 DOI: 10.1038/cddis.2017.461
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