Amit Singhal

Employment

• University of Massachusetts Chan Medical School Adjunct Associate Professor
  2023 - Present
• A*STAR Infectious Diseases Labs Senior Principal Investigator
  2021 - Present
• Singapore Immunology Network Principal Investigator
  2017 - Present
• Lee Kong Chian School of Medicine Adjunct Associate Professor
  2016 - Present
• Singapore Immunology Network Project Leader
  2014 - 2017
• Singapore Immunology Network Senior Research Scientist
  2012 - 2017
• Singapore Immunology Network Research Scientist
  2010 - 2012
• Novartis Institute for Tropical Diseases Postdoctoral Fellow
  2008 - 2010
• Institute Pasteur Brussels Scientific Researcher (Postdoc)
  2007 - 2008

Education

• All India Institute of Medical Sciences PhD
  2001 - 2007
• National Dairy Research Institute MSc Darying in Animal Biotechnology
  1997 - 2000
• Kurukshetra University BSc Biochmistry
  1994 - 1997

Projects & Funding

Projects & funding information is unavailable.

Publications (49)

• NR4A1 limits CD8⁺ T Cell effector responses and protection in tuberculosis
  2026 DOI: 10.21203/rs.3.rs-8363336/v1
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• The effect of metformin on the pharmacokinetics of rifampicin, isoniazid, and pyrazinamide in adults with tuberculosis
  Antimicrobial Agents and Chemotherapy 2026 DOI: 10.1128/aac.00748-26
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• Epigenetic imprinting of infant immunity by prenatal SARS-CoV-2
  2025 DOI: 10.21203/rs.3.rs-8150998/v1
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• Primary tuberculous mycobacterial granulomas provide a niche for superinfecting Mycobacterium abscessus
  Nature Communications 2025 DOI: 10.1038/s41467-025-65797-7
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• The repurposed STAT3 inhibitor pyrimethamine controls mycobacterial infection-induced vascular permeability and mycobacterial burden
  Biomedicine & Pharmacotherapy 2025 DOI: 10.1016/j.biopha.2025.118464
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• A Mycobacterium tuberculosis secreted virulence factor Rv1435c/hsr1 disrupts host snRNP biogenesis.
  Proceedings of the National Academy of Sciences of the United States of America 2025 DOI: 10.1073/pnas.2423349122
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• Inducible antibacterial responses in macrophages.
  Nature reviews. Immunology 2024 DOI: 10.1038/s41577-024-01080-y
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• Fetal liver CD34+ contain human immune and endothelial progenitors and mediate solid tumor rejection in NOG mice.
  Stem cell research & therapy 2024 DOI: 10.1186/s13287-024-03756-7
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• Histone acetylome-wide associations in immune cells from individuals with active Mycobacterium tuberculosis infection.
  Nature microbiology 2022 DOI: 10.1038/s41564-021-01049-w
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• Doxycycline host-directed therapy in human pulmonary tuberculosis
  Journal of Clinical Investigation 2021 DOI: 10.1172/jci141895
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