Subba Rao Gangi Setty

About

My laboratory studies the biogenesis of endocytic organelles, including specialized lysosome-related organelles in human cells. In particular, we focus on mechanisms of cargo segregation, vesicle biogenesis and transport, and vesicle fusion in healthy cells and their alterations in diseased conditions.

Employment

• Indian Institute of Science Bangalore Professor
  2022 - Present
• Indian Institute of Science Associate Professor
  2016 - 2022
• Indian Institute of Science Assistant Professor
  2010 - 2016
• Proteostasis Therapeutics Inc Senior Scientist
  2009 - 2010
• University of Pennsylvania Senior Research Investigator
  2004 - 2009
• University of Pennsylvania Postdoctoral Fellow
  2001 - 2004

Education

• Jawaharlal Nehru University PhD
  1996 - 2001
• Banaras Hindu University M Sc
  1994 - 1996

Projects & Funding

Projects & funding information is unavailable.

Publications (29)

• Syntaxin 3 SPI-2 dependent crosstalk facilitates the division of Salmonella containing vacuole.
  Traffic (Copenhagen, Denmark) 2023 DOI: 10.1111/tra.12887
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• Pseudophosphatase STYXL1 depletion enhances glucocerebrosidase trafficking to lysosomes via ER stress.
  Traffic (Copenhagen, Denmark) 2023 DOI: 10.1111/tra.12886
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• KIF13A—A Key Regulator of Recycling Endosome Dynamics
  Frontiers in Cell and Developmental Biology 2022 DOI: 10.3389/fcell.2022.877532
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• The Microscopy-Based Assay to Study and Analyze the Recycling Endosomes using SNARE Trafficking
  Journal of Visualized Experiments 2022 DOI: 10.3791/63087
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• Epidermal Lamellar Body Biogenesis: Insight Into the Roles of Golgi and Lysosomes
  Frontiers in Cell and Developmental Biology 2021 DOI: 10.3389/fcell.2021.701950
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• KIF13A motors are regulated by Rab22A to function as weak dimers inside the cell.
  Science advances 2021 DOI: 10.1126/sciadv.abd2054
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• Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
  Autophagy 2021 DOI: 10.1080/15548627.2020.1797280
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• Keratinocyte differentiation promotes ER stress-dependent lysosome biogenesis.
  Cell death & disease 2019 DOI: 10.1038/s41419-019-1478-4
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• Rab22A recruits BLOC-1 and BLOC-2 to promote the biogenesis of recycling endosomes.
  EMBO reports 2018 DOI: 10.15252/embr.201845918
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• Rab4A organizes endosomal domains for sorting cargo to lysosome-related organelles.
  Journal of cell science 2018 DOI: 10.1242/jcs.216226
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