Mukul K Midha

About

I am a Research Scientist at the Institute for Systems Biology, Seattle. My research is focused on understanding the early events along with temporal dynamics that activate the development of metabolic disorders using different quantitative proteomics strategies, in particular with high-resolution mass spectrometry. I have built a comprehensive spectral library to quantify the Escherichia coli proteome by DIA-MS. In addition, I contributed to building DIALib-QC, an assessment bioinformatics tool for spectral libraries which ensures error-free and high-quality libraries are shared in the community. During my Ph.D., I studied the molecular mechanism associated with obesity and diabetes signaling pathways in mouse models and received my Ph.D. from the Immunology Department, International Centre for Genetic Engineering and Biotechnology, India in 2013. Post Ph.D., I worked on understanding the absolute quantification of mycobacterial proteins during human macrophage infection. My background in biochemistry and proteomics has been very useful in working with complex biological samples such as bacteria, tissues, blood plasma, and serum. As a trained proteomics analytical biochemist, I standardize and implement different chromatography & MS setups and benchmark different data analysis tools in the field of label-free quantitative proteomics to achieve deeper proteome coverage and accurate quantitation of the proteins.

Employment

Employment history is unavailable.

Education

• International Centre for Genetic Engineering and Biotechnology Ph.D.
  2009 - 2013
• Jaipur National University Masters
  2007 - 2009
• University of Delhi Bachelors
  2004 - 2007

Projects & Funding

Projects & funding information is unavailable.

Publications

Publications are unavailable.