QURAT UL AIN
Also known as: Qurat
University of California, San Francisco, Hamdard University, International Center for Chemical and Biological Sciences, University of Karachi, Hamdard University Faculty of Pharmacy
About
Currently, Dr. Ain is working as a postdoctoral scholar at the Department of Pathology, University of California, San Francisco, USA. Where she is spatially characterizing the tumor microenvironment using NanoString's GeoMax Digital Spatial Profiling (DSP) Technology. In addition, she developed a human esophageal organoid model and optimized an organotypic air-liquid interface (ALI) model system and genetically modifying them through CRISPR-CAS technology.
As a part of CRUK-GC-Stroming Cancer Team at the University of California, San Francisco, she utilized single-cell RNA sequencing (scRNA-seq) and gene expression analysis to determine the effects of chronic and acute bile acid (BA) exposure on the transcriptional reprogramming of fibroblasts, leading to the production of pro-inflammatory cytokines.
Dr. Ain has been served as an Assistant Professor of Biochemistry/Pharmaceutical Chemistry at the Department of Pharmaceutical Chemistry, Faculty of Pharmacy Hamdard University, Karachi, Pakistan and as a Visiting Assistant Professor of Molecular Biology/Genetics at the Department of Physical Therapy, Faculty of Health & Medicine, Hamdard University, Karachi, Pakistan.
Dr. Ain received a Ph. D. in Molecular Medicine from Dr. Panjwni Center for Molecular Medicine & Drug Research, International Center for Chemical & Biological Sciences, University of Karachi, Pakistan in Collaboration with Department of Dermatology & Allergic Disease University of Ulm Germany.
Dr. Ain Ph.D. research was focus on the investigation of the role of deregulated oxidative stress and kinase dependent signal transduction pathways and their related genes involved in the multiple types of cancers initiation and progression with the goal of discovery and development of new anticancer therapeutics.
She also has a background in neurological, metabolic and cardiovascular diseases, most particularly understanding the molecular pathways of Parkinson’s, Type-II diabetes and cardiovascular diseases, she worked for the identification of new therapeutic targets, biomarkers, and development of relative therapeutics.
Employment
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University of California, San Francisco Postdoctoral Scholar2022 - 2026
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Hamdard University Visiting Assistant Professor2021 - 2022
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Hamdard University Faculty of Pharmacy Assistant Professor2020 - 2022
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International Center for Chemical and Biological Sciences Research Officer2009 - 2010
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International Center for Chemical and Biological Sciences Research Officer2008 - 2009
Education
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International Center for Chemical and Biological Sciences Ph. D.2016 - 2019
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International Center for Chemical and Biological Sciences M.Phil2010 - 2016
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University of Karachi Bachelors/ B. Pharmacy1999 - 2007
Projects & Funding
Projects & funding information is unavailable.
Publications (26)
- Abstract 6853: Spatial proteomic and transcriptomic characterization of the inflammatory landscape of formalin fixed paraffin embedded Barrett’s esophagus tissues Save
- Refining definitions of Barrett’s oesophagus to improve clinical resource utilisation Save
- Feasibility Study Utilizing NanoString’s Digital Spatial Profiling (DSP) Technology for Characterizing the Immune Microenvironment in Barrett’s Esophagus Formalin-Fixed Paraffin-Embedded Tissues Save
- Benzophenone Semicarbazones as Potential alpha-glucosidase and Prolyl Endopeptidase Inhibitor: In-vitro free radical scavenging, enzyme inhibition, mechanistic, and molecular docking studies Save
- Feasibility Study Utilizing NanoString’s Digital Spatial Profiling (DSP) Technology for Characterizing the Immune Microenvironment in Barrett’s Esophagus FFPE Tissues Save
- Estimation of In-Vitro Free Radical Scavenging and Cytotoxic Activities of Thiocarbohydrazones Derivatives Save
- 1,1-Diphenyl-2-picrylhydrazyl and superoxide anion radical scavenging 1 activities of heterocyclic 2-oxo-1,2,3,4-tetrahydropyrimidines Save
- “IUBMB Wood Whelan Scholarship: A Prestigious Opportunity Worth Exploring” Save
- Dissecting Immune-Inflammatory Microenvironment in the Barrett’s Esophagus to Esophageal Adenocarcinoma Transition: A Nanostring GeoMx Pilot Study Save
- 3, 3′- (3, 5-DCPBC) Down-Regulates Multiple Phosphokinase Dependent Signal Transduction Pathways in Malignant Melanoma Cells through Specific Diminution of EGFRY1086 Phosphorylation Save