Zabeer Ahmed

About

Twenty years research experience in the area of drug design and discovery from herbal and synthetic sources. During this period actively worked on following important research projects:

I Development of traditional herbal drugs as Immunomodulators/Adaptogens.
II Development of anti-diabetic agents.
III Prospecting biodiversity for its chemistry and bioactivity.
IV Newer Scientific Herbal Preparation for Global Positioning.
V Herbal Based Preparations for Degenerative Disorders: Diabetes mellitus type II (NIDDM) with emphasis on insulin sensitization and Herboprint-A tool for standardization of herbal medicine.
VI Golden Triangle Partnership Programme.
VII Design, Synthesis of Novel Sugar-Oxasteroid-Quinones as Non-Steroidal Dissociated Glucocorticoid Receptor (GR) Agonists for Rheumatoid Arthritis.
VIII Studied the Anti-inflammatory molecules from Boswellia serrata for Rheumatoid Arthritis.
IX Development of boswellic acid analogue as Anti-arthritic agent through combinatorial approach.

Employment

• Indian Institute of Integrative Medicine Senior Principal Scientist

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (12)

• Evaluation of the immunomodulatory and anti-inflammatory activity of Bakuchiol using RAW 264.7 macrophage cell lines and in animal models stimulated by lipopolysaccharide (LPS).
  International immunopharmacology 2020 DOI: 10.1016/j.intimp.2020.107264
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• Acteoside ameliorates inflammatory responses through NFkB pathway in alcohol induced hepatic damage
  International Immunopharmacology 2019 DOI: 10.1016/j.intimp.2019.01.020
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• Murrayanine Attenuates Lipopolysaccharide‐induced Inflammation and Protects Mice from Sepsis‐associated Organ Failure
  Basic & Clinical Pharmacology & Toxicology 2019 DOI: 10.1111/bcpt.13032
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• Correction: Four new carbazole alkaloids from Murraya koenigii that display anti-inflammatory and anti-microbial activities.
  Organic & biomolecular chemistry 2018 DOI: 10.1039/c8ob90030b
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• Kaempferol-3-o-β-d-glucuronate exhibit potential anti-inflammatory effect in LPS stimulated RAW 264.7 cells and mice model.
  International immunopharmacology 2018 DOI: 10.1016/j.intimp.2018.01.041
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• The amino analogue of β-boswellic acid efficiently attenuates the release of pro-inflammatory mediators than its parent compound through the suppression of NF-κB/IκBα signalling axis.
  Cytokine 2017 DOI: 10.1016/j.cyto.2017.12.004
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• Biopharmaceutic parameters, pharmacokinetics, transport and CYP-mediated drug interactions of IIIM-017: A novel nitroimidazooxazole analogue with anti-tuberculosis activity.
  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2017 DOI: 10.1016/j.ejps.2017.05.053
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• Anti-inflammatory potential of hentriacontane in LPS stimulated RAW 264.7 cells and mice model.
  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 DOI: 10.1016/j.biopha.2017.05.063
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• Preclinical comprehensive physicochemical and pharmacokinetic profiling of novel nitroimidazole derivative IIIM-019 - A potential oral treatment for tuberculosis.
  Pulmonary pharmacology & therapeutics 2016 DOI: 10.1016/j.pupt.2016.06.009
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• Four new carbazole alkaloids from Murraya koenigii that display anti-inflammatory and anti-microbial activities.
  Organic & biomolecular chemistry 2016 DOI: 10.1039/c6ob00267f
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