jagannatha Rao kosagisharaf
Institute for Scientific Research and Technology Services (INDICASAT), Medical University of South Carolina, Sri Venkateswara University, University of Virginia
About
Dr. Jagannatha Rao was born on 1st June 1956 in India. Dr.Rao had his Masters and Ph.D from Sri Venkateswara University, India. He is currently Director, Institute for Scientific Research and Technology Services (INDICASAT-AIP), Distinguished Scientist, Building 219, Clayton, City of Knowledge, Republic of Panamá. Member of National Bioethics Committee in Republic Panama. Dr.Rao also Adjunct faculty of Biomedical Informatics, University of Texas Health Sciences, Advisory Board Member of minority scholarship in UTCU- El Paso, USA. His research fields of specializations are: Mechanisms of proteins conformations in neurodegenerative disorders, DNA dynamics in neurodegenerative brain, Development of Alzheimer’s and traumatic brain injury animal models; Aluminium Neurotoxicology; Biomarkers; Neuronutraceuticals. Dr.Rao is on the Editorial board member of 25 journals. Guided 20 Ph.D and 8 postdoctoral fellows. Also was on the International review board of Parkinson disease association UK, France Mental health grant program, and Department of Biotechnology, India. He is the Fellow of National Academy of Sciences (India), Linnaean Society (UK), Association of Biotechnology and Pharmacy . He is the guest editor for two special issues of journals on Alzheimer´s disease. He has international collaborations with scientists in USA, UK, Italy, Germany, China, Japan. He has published 125 papers and 6 book chapters. Professional contributions: Biomarkers in brain disorders: Diet, Nutrition and disease with reference to brain disorders, MRI studies on depression and Alzheimer’s patients, Also involved on blood DNA bank on depression and brain bank on depression, Also involved on drug trials in bipolar disorders, Leading a research team on indigenous medicines as alternate therapies for Alzheimer’s and Psoriasis, Pharmacokinetics of molecules and clinical studies of drugs in neuropsychiatry, Trace metals homeostasis in Bipolar and Alzheimer’s and Parkinson disease, Amyloid 42/40, ceruloplasmin, transferring, synuclein in plasma, 8-hydroxy-guanosine as maker in serum and CSF, Strongly Interacting with NIH foundation on Biomarkers, Animal models: Developed animal model to imprint neurodegeneration after traumatic brain injury, Development of non-transgenic environmentally induced Aged Rabbit as Alzheimer’s animal model. Neuronutririon: Nutrition neuroscience is an emerging discipline shedding light on the fact that nutritional factors are intertwined with human cognition, behavior and emotions. Molecular neuroscience: DNA stability in Alzheimer’s, Parkinson and Depression brains, Amyloid and Synuclein aggregation and mathematical modeling of aggregation, A new concept on Protein-DNA complexes in neurodegeneration, Trace metals in neurodegeneration. He was Visiting Scientist at University of Siena, Italy, DBT overseas Associate University of Virginia, USA, Visiting Scientist, University of Virginia, USA,, Visiting Scientist, Medical University of South Carolina, USA.
Employment
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Institute for Scientific Research and Technology Services (INDICASAT) Director and Distinguished Scientist2010 - Present
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Medical University of South Carolina Visiting Scientist2007 - 2008
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University of Virginia DBT visiting Scientist1996 - 1998
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Central Food Technological Research Institute CSIR Scientist to Senior Scientist1987 - 2010
Education
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Sri Venkateswara University Ph.D1980 - 1984
Projects & Funding
Projects & funding information is unavailable.
Publications (125)
- Revisiting Metal Toxicity in Neurodegenerative Diseases and Stroke: Therapeutic Potential Save
- A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods. Save
- The lipid content and fatty acid composition of four eastern central Pacific native fish species Save
- α-Synuclein Misfolding Versus Aggregation Relevance to Parkinson's Disease: Critical Assessment and Modeling. Save
- Polyphenols as Therapeutic Molecules in Alzheimer's Disease Through Modulating Amyloid Pathways. Save
- Comparative study on anti-oxidant and anti-inflammatory activities of Caesalpinia crista and Centella asiatica leaf extracts. Save
- In vitro evidence that an aqueous extract of Centella asiatica modulates α-synuclein aggregation dynamics. Save
- New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases. Save
- The effects of impaired cerebral circulation on Alzheimer's disease pathology: evidence from animal studies. Save
- Studies on serum 8-hydroxy guanosine (8-OHdG) as reliable biomarker for psoriasis. Save