GY
Guang Yang
University of New South Wales - Randwick Campus, The University of Sydney, Chinese Academy of Sciences Shanghai Institute of Nutrition and Health, Fudan University
Research areas: Chemistry · Inorganic Chemistry · Crystal structures of chemical compounds · Crystal Structures and Properties · Crystallography and molecular interactions
0000-0003-4377-1836
Employment
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University of New South Wales - Randwick Campus Senior Research Associate2021 - Present
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University of Sydney Research Fellow2014 - 2021
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Garvan Institute of Medical Research Research Officer2010 - 2014
Education
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Chinese Academy of Sciences Shanghai Institute of Nutrition and Health Doctor2003 - 2010
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Fudan University Bachelor1999 - 2003
Projects & Funding
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Unravelling a canonical mitochondrial stress response pathway Australian Research Council2021 - 2023
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Partnership Collaboration Awards (PCA) The University of Sydney and Zhejiang University Zhejiang University2020 - 2020
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Novel function of insulin in regulating mTOR signalling. National Health and Medical Research Council2012 - 2013
Publications (29)
- CRISPRi screening in cultured human astrocytes uncovers distal enhancers controlling genes dysregulated in Alzheimer’s disease Save
- Phosphatidylserine transporters ORP5 and ORP8 control cholesterol trafficking from the plasma membrane to the endoplasmic reticulum Save
- CHP1 promotes lipid droplet growth and regulates the localization of key enzymes for triacylglycerol synthesis Save
- Personalized phosphoproteomics of skeletal muscle insulin resistance and exercise links MINDY1 to insulin action Save
- Structural insights into Ras regulation by SIN1 Save
- Personalized phosphoproteomics identifies functional signaling Save
- Dissecting the biology of mTORC1 beyond rapamycin Save
- Dynamic modelling of the PI3K/MTOR signalling network uncovers biphasic dependence of mTORC1 activity on the mTORC2 subunit SIN1 Save
- Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis Save
- CASK modulates the assembly and function of the Mint1/Munc18-1 complex to regulate insulin secretion Save
- Dynamic modelling of the PI3K/mTOR signalling network uncovers biphasic dependence of mTORC1 activation on the mTORC2 subunit Sin1 Save
- Global redox proteome and phosphoproteome analysis reveals redox switch in Akt Save
- RagC phosphorylation autoregulates mTOR complex 1 Save
- Membrane Topology of Trafficking Regulator of GLUT4 1 (TRARG1) Save
- A novel PHD-finger protein 14/KIF4A complex overexpressed in lung cancer is involved in cell mitosis regulation and tumorigenesis Save
- Combination of mTOR inhibitors augments potency while activating PI3K signaling in pituitary tumors Save
- A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation Save
- Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry Save
- Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo Save
- Depletion of PHF14, a novel histone-binding protein gene, causes neonatal lethality in mice due to respiratory failure Save